Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection

被引：6
|
作者：
Liao, Po-Wei [1 ]
Teng, Chieh-Lin Jerry [1 ,2 ,3 ]
Chou, Cheng-Wei [1 ,4 ]
机构：
[1] Taichung Vet Gen Hosp, Dept Internal Med, Div Hematol Med Oncol, Taichung 40705, Taiwan
[2] Tunghai Univ, Dept Life Sci, Taichung 40705, Taiwan
[3] Chung Shan Med Univ, Sch Med, Taichung 40705, Taiwan
[4] China Med Univ, Grad Inst Biomed Sci, Taichung 40705, Taiwan
来源：
VACCINES | 2021年 / 9卷 / 12期
关键词：
SARS-CoV-2; immune thrombocytopenia; adenovirus vaccine; ischemic stroke; COVID-19; PRACTICES INTERIM RECOMMENDATION; COVID-19; VACCINE; ADVISORY-COMMITTEE; UNITED-STATES; PURPURA;
D O I：
10.3390/vaccines9121486
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We present a case of immune thrombocytopenia (ITP) induced by the chimpanzee adenovirus-vectored vaccine, without evidence of thrombosis, eight days after vaccine administration. The thrombocytopenia condition improved after administering steroid treatment. This adenovirus vaccine had been reported to induce rare side effects, such as immune thrombotic thrombocytopenia. This case report showed that it could also induce immune thrombocytopenia without the presence of thrombosis. Therefore, we should be cautious of this rare side effect as global vaccine administrations against coronavirus disease increase.
引用
收藏
页数：6
相关论文
共 50 条
  • [21] Immunogenicity of an adenovirus-vectored bivalent vaccine against wild type SARS-CoV-2 and Omicron variants in a murine model (vol 42, pg 1292, 2024)
    Ji, Yuanyuan
    Sui, Xiuwen
    Miao, Wei
    Wang, Chang
    Wang, Qing
    Duan, Zhuojun
    Wei, Bochao
    Wu, Dan
    Wei, Menghan
    Shao, Juan
    Zheng, Xiuyu
    Zhu, Tao
    VACCINE, 2024, 42 (14) : 3374 - 3374
  • [22] Immunogenicity and efficacy of a chimpanzee adenovirus-vectored Rift Valley Fever vaccine in mice
    Warimwe, George M.
    Lorenzo, Gema
    Lopez-Gil, Elena
    Reyes-Sandoval, Arturo
    Cottingham, Matthew G.
    Spencer, Alexandra J.
    Collins, Katharine A.
    Dicks, Matthew D. J.
    Milicic, Anita
    Lall, Amar
    Furze, Julie
    Turner, Alison V.
    Hill, Adrian V. S.
    Brun, Alejandro
    Gilbert, Sarah C.
    VIROLOGY JOURNAL, 2013, 10
  • [23] The role of vaccination route with an adenovirus-vectored vaccine in protection, viral control, and transmission in the SARS-CoV-2/K18-hACE2 mouse infection model
    Dickson, Alexandria
    Geerling, Elizabeth
    Stone, E. Taylor
    Hassert, Mariah
    Steffen, Tara L.
    Makkena, Taneesh
    Smither, Madeleine
    Schwetye, Katherine E.
    Zhang, Jianfeng
    Georges, Bertrand
    Roberts, M. Scot
    Suschak, John J.
    Pinto, Amelia K.
    Brien, James D.
    FRONTIERS IN IMMUNOLOGY, 2023, 14
  • [24] Both chimpanzee adenovirus-vectored and DNA vaccines induced long-term immunity against Nipah virus infection
    Lu, Mingqing
    Yao, Yanfeng
    Zhang, Xuekai
    Liu, Hang
    Gao, Ge
    Peng, Yun
    Chen, Miaoyu
    Zhao, Jiaxuan
    Zhang, Xiaoyu
    Yin, Chunhong
    Guo, Weiwei
    Yang, Peipei
    Hu, Xue
    Rao, Juhong
    Li, Entao
    Chen, Tong
    Chiu, Sandra
    Wong, Gary
    Yuan, Zhiming
    Lan, Jiaming
    Shan, Chao
    NPJ VACCINES, 2023, 8 (01)
  • [25] Both chimpanzee adenovirus-vectored and DNA vaccines induced long-term immunity against Nipah virus infection
    Mingqing Lu
    Yanfeng Yao
    Xuekai Zhang
    Hang Liu
    Ge Gao
    Yun Peng
    Miaoyu Chen
    Jiaxuan Zhao
    XiaoYu Zhang
    Chunhong Yin
    Weiwei Guo
    Peipei Yang
    Xue Hu
    Juhong Rao
    Entao Li
    Tong Chen
    Sandra Chiu
    Gary Wong
    Zhiming Yuan
    Jiaming Lan
    Chao Shan
    npj Vaccines, 8
  • [26] Oral vaccination with an adenovirus-vectored vaccine protects against botulism
    Chen, Shan
    Xu, Qingfu
    Zeng, Mingtao
    VACCINE, 2013, 31 (07) : 1009 - 1011
  • [27] Homologous or heterologous administration of mRNA or adenovirus-vectored vaccines show comparable immunogenicity and effectiveness against the SARS-CoV-2 Omicron variant
    Pastore, Gabiria
    Polvere, Jacopo
    Fiorino, Fabio
    Lucchesi, Simone
    Montesi, Giorgio
    Rancan, Ilaria
    Zirpoli, Sara
    Lippi, Arianna
    Durante, Miriam
    Fabbiani, Massimiliano
    Tumbarello, Mario
    Montagnani, Francesca
    Medaglini, Donata
    Ciabattini, Annalisa
    EXPERT REVIEW OF VACCINES, 2024, 23 (01) : 432 - 444
  • [28] Recurrence of immune thrombocytopenia at the time of SARS-CoV-2 infection
    Michele Merli
    Walter Ageno
    Fausto Sessa
    Marco Salvini
    Domenica Caramazza
    Barbara Mora
    Agostino Rossi
    Cristina Rovelli
    Francesco Passamonti
    Paolo Grossi
    Annals of Hematology, 2020, 99 : 1951 - 1952
  • [29] Immune thrombocytopenia in the setting of acute SARS-CoV-2 infection
    Alves, M. Eduarda Caseiro
    Carmo, Filipa
    Malato, Madalena
    Cunha, Florbela
    BMJ CASE REPORTS, 2023, 16 (06)
  • [30] Recurrence of immune thrombocytopenia at the time of SARS-CoV-2 infection
    Merli, Michele
    Ageno, Walter
    Sessa, Fausto
    Salvini, Marco
    Caramazza, Domenica
    Mora, Barbara
    Rossi, Agostino
    Rovelli, Cristina
    Passamonti, Francesco
    Grossi, Paolo
    ANNALS OF HEMATOLOGY, 2020, 99 (08) : 1951 - 1952
12345