A new cytotoxic benzophenanthridine isoquinoline alkaloid from the fruits of Macleaya cordata

被引：7
|
作者：
Zou, Hui-Liang [1 ]
Li, Hong-Yu [1 ]
Liu, Bai-Lian [1 ]
Zhou, Guang-Xiong [1 ]
机构：
[1] Jinan Univ, Inst Tradit Chinese Med & Nat Prod, Guangdong Prov Key Lab Pharmacodynam Constituents, Coll Pharm, Guangzhou 510632, Guangdong, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2015年 / 17卷 / 08期
关键词：
Macleaya cordata; benzophenanthridine alkaloid; cordatine;
D O I：
10.1080/10286020.2015.1016000
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A new cytotoxic benzophenanthridine isoquinoline alkaloid, named cordatine (1), together with one known alkaloid 8-methoxydihydrochelerythrine (2), was isolated from the fruits of Macleaya cordata. The structure of the new compound was elucidated by spectroscopic methods including 1D and 2D NMR, HR-ESI-MS. Both compounds indicated significant cytotoxicity against MCF-7 and SF-268 cell lines.
引用
收藏
页码：856 / 860
页数：5
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