The two-stage clonal expansion model as an example of a biologically based model of radiation-induced cancer

被引：0

作者：

Heidenreich, WF ^{[1
]}

Paretzke, HG ^{[1
]}

机构：

[1] GSF, Inst Radiat Protect, D-85758 Neuherberg, Germany

来源：

RADIATION RESEARCH | 2001年 / 156卷 / 05期

关键词：

D O I：

10.1667/0033-7587(2001)156[0678:TTSCEM]2.0.CO;2

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A model with two stages and clonal expansion (TSCE) is reviewed as a prototype for biologically based models of cancer development. Applications of the TSCE model to data sets for animals and humans for particle radiation (a particles) are presented. The results suggest that the radiation not only influences the initiating mutation, but may also act as a promoter. A possible mechanism for the promoting action is described. The consequences of these results for the shapes of the radiation dose-response curves at low doses and dose rates are discussed. (C) 2001 by Radiation Research Society.

引用

页码：678 / 681

页数：4

共 50 条

[21] A two-stage prognosis model in condition based maintenance
Wang, Wenbin
EUROPEAN JOURNAL OF OPERATIONAL RESEARCH, 2007, 182 (03) : 1177 - 1187
[22] An Efficiency Measurement Model Based on Two-stage DEA
Cheng, Dayou
SEVENTH WUHAN INTERNATIONAL CONFERENCE ON E-BUSINESS, VOLS I-III, 2008, : 1932 - 1937
[23] STUDY ON INTEGRATION MODEL BASED ON TWO-STAGE TRANSFORMATION
Li Huayang
Gui Hao
Yi Baolin
2007 INTERNATIONAL CONFERENCE ON WIRELESS COMMUNICATIONS, NETWORKING AND MOBILE COMPUTING, VOLS 1-15, 2007, : 6238 - +
[24] Causality extraction model based on two-stage GCN
Guangli Zhu
Zhengyan Sun
Shunxiang Zhang
Subo Wei
KuanChing Li
Soft Computing, 2022, 26 : 13815 - 13828
[25] Two-Stage Model of Chemically Induced Hepatocellular Carcinoma in Mouse
Luo, Min
Yang, Fan
Huang, Sheng-xin
Kuang, Zhi-peng
Luo, Xiao-ling
Li, Yuan-dong
Wu, Ji-ning
Xie, Yu-an
ONCOLOGY RESEARCH, 2012, 20 (11) : 517 - 528
[26] TWO-STAGE MODEL OF NANOCONES FORMED ON A SURFACE OF SEMICONDUCTORS BY LASER RADIATION
Medvid', A.
RADIATION INTERACTION WITH MATERIAL AND ITS USE IN TECHNOLOGIES 2012, 2012, : 48 - 50
[27] A numerical solution to the nonhomogeneous two-stage MVK model of cancer
Crump, KS
Subramaniam, RP
Van Landingham, CB
RISK ANALYSIS, 2005, 25 (04) : 921 - 926
[28] A Two-Stage Earthquake Event Classification Model Based on Diffusion Probability Model
Meng, Fanchun
Ren, Tao
Wang, Pengyu
Liu, Xinliang
Xiang, Wenjuan
He, Xinyu
IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING, 2024, 62
[29] The Dynamic Model for Cancer Relapse Based on Two-Stage Model of Carcinogenesis (vol 41, pg 1701, 2012)
Kao, Lie-Jane
Chen, Li-Shya
COMMUNICATIONS IN STATISTICS-THEORY AND METHODS, 2012, 41 (22) : 4222 - 4222
[30] Biophysical modelling of the effects of inhaled radon progeny on the bronchial epithelium for the estimation of the relationships applied in the two-stage clonal expansion model of carcinogenesis
Madas, Balazs G.
Varga, Katalin
RADIATION PROTECTION DOSIMETRY, 2014, 159 (1-4) : 237 - 241

← 1 2 3 4 5 →