A detailed chemical composition and antimicrobial activity of Hypericum richeri Vill. subsp grisebachii (Boiss.) Nyman essential oil from Serbia

被引:0
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作者
Dordevic, Aleksandra [1 ]
Zlatkovic, Bojan [2 ]
Lazarevic, Jelena [3 ]
Palic, Radosav [1 ]
机构
[1] Univ Nis, Dept Chem, Fac Sci & Math, Nish 18000, Serbia
[2] Univ Nis, Dept Biol & Ecol, Fac Sci & Math, Nish 18000, Serbia
[3] Univ Nis, Dept Pharm, Fac Med Sci, Nish 18000, Serbia
来源
关键词
Hypericum richeri subsp grisebachii; essential oil composition; antimicrobial activity; germacrene D; dodecanal; EXTRACTS; L;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The essential oil of fresh aerial parts of Hypericum richeri subsp. grisebachii obtained by hydrodistillation was analyzed by gas chromatography (GC) and gas chromatography/mass spectral GC/MS. One hundred and five constituents identified accounted for 96.1% of the total oil. The major components of the oil were: germacrene D (13.1%), dodecanal (11.9%), beta-caryophyllene (7.4%), beta-pinene (5.8%), caryophyllene oxide (4.2%) and (E)-beta-ocimene (3.3%). The volatile profile of H. richeri subsp. grisebachii was characterized by a large amount of sesquiterpenoids (56.2%), especially by hydrocarbons of this fraction (34.1%). The in vitro antimicrobial activity of essential oil was also examined against a panel of microbial strains by broth microdilution assay and it was found to have moderate effect against all tested microorganisms.
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页码:5486 / 5492
页数:7
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