In-fiber integrated microfluidic sensor based on optical fiber with suspended core

We report an in-fiber integrated chemiluminiscence sensor based on a kind of hollow optical fiber with a suspended inner core. The path of mircofluid is realized by etching microholes for inlets and outlets on the surface of the optical fiber without damaging the inner core and then constructing a melted point beside the microhole of the outlet. By injecting samples into the fiber, the liquids can be fully mixed and form steady microflows. Simultaneously, the photon emitted from the chemiluminiscence reaction is efficiently coupled into the core and can be detected at the end of the optical fiber.