Cholesteryl ester transfer protein (CETP) gene and cholesterol metabolism in dementia

被引:0
|
作者
Fernandez-Novoa, L. [1 ,2 ]
Llovo, R. [1 ,2 ]
Seoane, S. [1 ,2 ]
Corzo, L. [3 ,4 ]
Cacabelos, R. [3 ,4 ]
机构
[1] EBIOTEC, Dept Mol Genet, Parcela A-06,Nave F, Bergondo 15165, A Coruna, Spain
[2] EBIOTEC, Dept Genom, Bergondo 15165, A Coruna, Spain
[3] EuroEspes Biomed Res Ctr, Dept Clin Neurosci, Bergondo 15166, La Coruna, Spain
[4] EuroEspes Biomed Res Ctr, Dept Clin Chem, Bergondo 15166, La Coruna, Spain
关键词
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
A link between cholesterol and the development of Alzheimer disease (AD) has been proposed and many investigations have established a connection between AD and cholesterol dysregulation (1.). Many genes related to cholesterol homeostasis have been associated with Alzheimer disease (AD) (2), including the CETP gene (3, 4). We have studied the Taq1B polymorphism of the CETP gene in AD and Control subjects and its influence on blood lipid parameters.
引用
收藏
页码:31 / +
页数:3
相关论文
共 50 条
  • [31] A polymorphism of the gene coding for cholesterol ester transfer protein (CETP) that affects transfer of plasma cholesterol ester and its sensitivity to regulation
    GirardGloba, A
    BIOMEDICINE & PHARMACOTHERAPY, 1997, 51 (09) : 404 - 405
  • [32] A polymorphic site in the 3' untranslated region of the cholesteryl ester transfer protein (CETP) gene is associated with low CETP activity
    Tamminen, M
    Kakko, S
    Kesaniemi, YA
    Savolainen, MJ
    ATHEROSCLEROSIS, 1996, 124 (02) : 237 - 247
  • [33] Two novel mutations of cholesteryl ester transfer protein (CETP) gene in Japanese hyperalphalipoproteinemic patients
    Sakai, N
    Arai, T
    Maruyama, T
    Yamashita, S
    SantamarinaFojo, S
    Brewer, HB
    Matsuzawa, Y
    ATHEROSCLEROSIS, 1997, 134 (1-2) : 373 - 373
  • [34] Synthesis of novel β-propanamides to inhibit cholesteryl ester transfer protein(CETP)
    Hong-Lei Xie
    Chun-Chi Liu
    Yi-Qun Li
    Chang-Lin Bai
    Chen-Zhou Hao
    Jing Guo
    Chang-Qun Luo
    Dong-Mei Zhao
    Mao-Sheng Cheng
    Chinese Chemical Letters, 2017, 28 (02) : 260 - 263
  • [35] Synthesis of novel β-propanamides to inhibit cholesteryl ester transfer protein (CETP)
    Xie, Hong-Lei
    Liu, Chun-Chi
    Li, Yi-Qun
    Bai, Chang-Lin
    Hao, Chen-Zhou
    Guo, Jing
    Luo, Chang-Qun
    Zhao, Dong-Mei
    Cheng, Mao-Sheng
    CHINESE CHEMICAL LETTERS, 2017, 28 (02) : 260 - 263
  • [36] The cholesteryl ester transfer protein (CETP) locus and protection against atherosclerosis
    Berg, K
    GENES AND RESISTANCE TO DISEASE, 2000, : 51 - 65
  • [37] Future of Cholesteryl Ester Transfer Protein (CETP) Inhibitors: A Pharmacological Perspective
    Mohammadpour, Amir Hooshang
    Akhlaghi, Fatemeh
    CLINICAL PHARMACOKINETICS, 2013, 52 (08) : 615 - 626
  • [38] Diphenylpyridylethanamine (DPPE) Derivatives as Cholesteryl Ester Transfer Protein (CETP) Inhibitors
    Harikrishnan, Lalgudi S.
    Finlay, Heather J.
    Qiao, Jennifer X.
    Kamau, Muthoni G.
    Jiang, Ji
    Wang, Tammy C.
    Li, James
    Cooper, Christopher B.
    Poss, Michael A.
    Adam, Leonard P.
    Taylor, David S.
    Chen, Alice Ye A.
    Yin, Xiaohong
    Sleph, Paul G.
    Yang, Richard Z.
    Sitkoff, Doree F.
    Galella, Michael A.
    Nirschl, David S.
    Van Kirk, Katy
    Miller, Arthur V.
    Huang, Christine S.
    Chang, Ming
    Chen, Xue-Qing
    Salvati, Mark E.
    Wexler, Ruth R.
    Lawrence, R. Michael
    JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (13) : 6162 - 6175
  • [39] Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease
    Amand F. Schmidt
    Nicholas B. Hunt
    Maria Gordillo-Marañón
    Pimphen Charoen
    Fotios Drenos
    Mika Kivimaki
    Deborah A. Lawlor
    Claudia Giambartolomei
    Olia Papacosta
    Nishi Chaturvedi
    Joshua C. Bis
    Christopher J. O’Donnell
    Goya Wannamethee
    Andrew Wong
    Jackie F. Price
    Alun D. Hughes
    Tom R. Gaunt
    Nora Franceschini
    Dennis O. Mook-Kanamori
    Magdalena Zwierzyna
    Reecha Sofat
    Aroon D. Hingorani
    Chris Finan
    Nature Communications, 12
  • [40] Cholesteryl Ester Transfer Protein (CETP) Inhibitors: Is There Life After Torcetrapib?
    Neeli, Hemanth
    Rader, Daniel J.
    CARDIOLOGY CLINICS, 2008, 26 (04) : 537 - +