Republished review: Next generation sequencing for clinical diagnostics and personalised medicine: implications for the next generation cardiologist

被引：0

作者：

Ware, James S. ^{[1
,2
]}

Roberts, Angharad M. ^{[1
]}

Cook, Stuart A. ^{[1
,3
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, MRC, Ctr Clin Sci, London W12 0NN, England

[2] Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, London W12 0NN, England

[3] Royal Brompton & Harefield NHS Trust, Cardiovasc Biomed Res Unit, London, England

来源：

POSTGRADUATE MEDICAL JOURNAL | 2012年 / 88卷 / 1038期

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

LONG-QT SYNDROME; NONINVASIVE PRENATAL-DIAGNOSIS; DILATED CARDIOMYOPATHY; FETAL DNA; CLOPIDOGREL; MUTATIONS; POLYMORPHISMS; GENOTYPE; EFFICACY; OUTCOMES;

D O I：

10.1136/pgmj.2011.300742rep

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The fast moving field of genomic medicine is already impacting on clinical care and cardiologists are fortunate to be in a position to benefit early from the transformative advances in genomics. However, the challenges associated with genomics in the clinic in general, and with next generation sequencing technologies in particular, are significant and cardiologists need to be prepared if they wish to surf the wave of genomic opportunity. This paper presents an overview of the implications of next generation sequencing for clinical diagnostics and personalised medicine in the cardiology clinic.

引用

页码：234 / 239

页数：6

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