Clinical perspectives on mesenchymal stem cells promoting wound healing in diabetes mellitus patients by inducing autophagy

被引：1

作者：

Han, Y. -F. ^{[1
]}

Sun, T. -J. ^{[2
]}

Han, Y. -Q. ^{[3
]}

Xu, G. ^{[1
]}

Liu, J. ^{[1
]}

Tao, R. ^{[4
]}

机构：

[1] Capital Med Univ, Affiliated Beijing Shijitan Hosp, Dept Plast Surg, Beijing, Peoples R China

[2] Peoples Liberat Army Gen Hosp, Hainan Branch, Dept Burn & Plast Surg, Sanya, Peoples R China

[3] Wuhan Inst Technol, Sch Elect & Informat Engn, Wuhan, Peoples R China

[4] Peoples Liberat Army Gen Hosp, Dept Plast Surg, Beijing, Peoples R China

来源：

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES | 2015年 / 19卷 / 14期

基金：

中国国家自然科学基金;

关键词：

Mesenchymal stem cells; Diabetes mellitus; Autophagy; Wound healing; Application; ANGIOGENESIS; INDUCTION; DISEASE;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

BACKGROUND: The pathogenesis of wound healing in diabetes mellitus is complicated, and results in less effective healing. Mesenchymal stem cells (MSCs) have been thought to promote wound healing in diabetes. However, the underlying mechanisms are not well understood. Autophagy plays an important role in wound healing. It has been speculated that the mesenchymal stem cells derived from the umbilical cord can improve wound healing in diabetes mellitus by inducing autophagy. Hence, we reviewed the research progress in this field to identify new strategies of clinical treatment for wound healing in diabetes mellitus.

引用

页码：2666 / 2670

页数：5

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