Seizures and Epilepsy in Autism Spectrum Disorder

被引：12

作者：

Besag, Frank M. C. ^{[1
,2
,3
]}

Vasey, Michael J. ^{[1
]}

机构：

[1] East London NHS Fdn Trust, 5-7 Rush Court, Bedford MK40 3JT, England

[2] UCL, London, England

[3] Kings Coll London, London, England

来源：

CHILD AND ADOLESCENT PSYCHIATRIC CLINICS OF NORTH AMERICA | 2020年 / 29卷 / 03期

关键词：

Epilepsy; Seizures; Epileptic encephalopathy; Autism; Regression; Intellectual disability; Genetics; DE-NOVO MUTATIONS; INFANTILE SPASMS; DRAVET-SYNDROME; MOUSE MODEL; MITOCHONDRIAL DYSFUNCTION; INTELLECTUAL DISABILITY; ANTIEPILEPTIC DRUGS; GENETIC LANDSCAPE; GABA(A) RECEPTOR; RISK-FACTORS;

D O I：

10.1016/j.chc.2020.02.002

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Epilepsy and autism frequently co-occur. Epilepsy confers an increased risk of autism and autism confers an increased risk of epilepsy. Specific epilepsy syndromes, intellectual disability, and female gender present a particular risk of autism in individuals with epilepsy. Epilepsy and autism are likely to share common etiologies, which predispose individuals to either or both conditions. Genetic factors, metabolic disorders, mitochondrial disorders, and immune dysfunction all can be implicated.

引用

页码：483 / +

页数：19

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