Time to re-evaluate the risks and benefits of valproate and a call for action

被引：3

作者：

Howes, Oliver D. ^{[1
,2
]}

Barnes, Thomas R. E. ^{[3
]}

Lennox, Belinda R. ^{[4
]}

Markham, Sarah ^{[5
]}

Natesan, Sridhar ^{[1
,2
]}

机构：

[1] Kings Coll London, Inst Psychiat Psychol & Neurosci, Psychosis Studies, London, England

[2] Imperial Coll London, Inst Clin Sci, Fac Med, London, England

[3] Imperial Coll London, Dept Brain Sci, Fac Med, London, England

[4] Univ Oxford, Dept Psychiat, Oxford, England

[5] Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Biostat & Hlth Informat, London, England

来源：

BRITISH JOURNAL OF PSYCHIATRY | 2022年 / 221卷 / 06期

关键词：

psychotic disorders; anticonvulsants; drug interactions and side-effects; polypharmacy; education and training;

D O I：

10.1192/bjp.2022.94

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Valproate is widely used in psychiatry and neurology, including off-label use. Here we consider its potential benefits and risks, particularly for women of childbearing potential, and the evidence that clinical guidelines are adhered to. Finally, we consider the implications for clinical practice and research into its efficacy in off-label indications.

引用

页码：711 / 713

页数：3

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