Signal-to-noise ratio analysis and improvement for fluorescence tomography imaging

被引：6

作者：

Wang, Huiquan ^{[1
,2
,3
]}

Feng, Xing ^{[1
]}

Shi, Boya ^{[1
,3
]}

Liang, Wenxuan ^{[2
]}

Chen, Yongping ^{[2
]}

Wang, Jinhai ^{[1
,3
]}

Li, Xingde ^{[2
]}

机构：

[1] Tianjin Polytech Univ, Sch Elect & Informat Engn, Tianjin 300387, Peoples R China

[2] Johns Hopkins Univ, Dept Biomed Engn, Baltimore, MD 21205 USA

[3] Tianjin Key Lab Optoelect Detect Technol & Syst, Tianjin 300387, Peoples R China

来源：

REVIEW OF SCIENTIFIC INSTRUMENTS | 2018年 / 89卷 / 09期

基金：

中国博士后科学基金; 美国国家卫生研究院;

关键词：

IN-VIVO; MOLECULAR TOMOGRAPHY; INDOCYANINE GREEN; X-RAY;

D O I：

10.1063/1.5045511

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

CCD-based fluorescence tomography is widely used for small animal whole-body imaging. In this report, systematic signal-to-noise ratio (SNR) analyses of a fluorescence tomography imaging (FTI) system were performed, resulting in an easy-to-follow strategy to optimize hardware configurations and operational conditions for acquiring high-quality imaging data and for improving the overall system performance. Phantom experiments were conducted to demonstrate the performance improvement by these optimizations. The improved performance was further verified by imaging a tumor-bearing mouse in vivo. This report provides general and practical guidelines for setting up a high-performance electron multiplying charge coupled device based FTI system to achieve an optimized SNR, which can be useful for future FTI technology development. Published by AIP Publishing.

引用

页数：10

共 50 条

[1] Signal-to-noise ratio analysis of the computed tomography imaging spectrometer
Volin, CE
Descour, MR
Dereniak, EL
IMAGING SPECTROMETRY IV, 1998, 3438 : 107 - 113
[2] Signal-to-noise ratio and signal-to-noise efficiency in SMASH imaging
Sodickson, DK
Griswold, MA
Jakob, PM
Edelman, RR
Manning, WJ
MAGNETIC RESONANCE IN MEDICINE, 1999, 41 (05) : 1009 - 1022
[3] Theoretical investigation of the signal-to-noise ratio in fluorescence lifetime imaging
Philip, J
Carlsson, K
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 2003, 20 (02): : 368 - 379
[4] Optical coherence tomography by "spectral radar":: Improvement of signal-to-noise ratio
Andretzky, P
Knauer, M
Kiesewetter, F
Häusler, G
COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICAL SCIENCE AND CLINICAL APPLICATIONS IV, 2000, 3915 : 55 - 59
[5] DOUBLE PULSE TRANSMISSION - SIGNAL-TO-NOISE RATIO IMPROVEMENT IN ULTRASOUND IMAGING
Trots, Ihor
Nowicki, Andrzej
Lewandowski, Marcin
Secomski, Wojciech
Litniewski, Jerzy
ARCHIVES OF ACOUSTICS, 2008, 33 (04) : 593 - 601
[6] Analysis of in-plane signal-to-noise ratio in computed tomography
Hara, Takanori
Ichikawa, Katsuhiro
Sanada, Shigeru
Ida, Yoshihiro
MEDICAL IMAGING 2008: PHYSICS OF MEDICAL IMAGING, PTS 1-3, 2008, 6913
[7] Signal-to-noise ratio improvement of EMCCD cameras
Zhang, Wen W.
Chen, Qian
Zhou, Bei B.
He, Wei J.
World Academy of Science, Engineering and Technology, 2010, 65 : 1152 - 1156
[8] IMPROVEMENT OF SIGNAL-TO-NOISE RATIO IN RESISTIVITY PROFILES
BERNABINI, M
BRIZZOLARI, E
PIRO, S
GEOPHYSICAL PROSPECTING, 1988, 36 (05) : 559 - 570
[9] NONLINEAR TECHNIQUES FOR THE IMPROVEMENT OF SIGNAL-TO-NOISE RATIO
SHINRIKI, M
IEEE TRANSACTIONS ON COMMUNICATIONS, 1986, 34 (09) : 969 - 973
[10] SIGNAL-TO-NOISE RATIO IMPROVEMENT IN A PCM SYSTEM
CLAVIER, AG
PANTER, PF
DITE, W
PROCEEDINGS OF THE INSTITUTE OF RADIO ENGINEERS, 1948, 36 (03): : 371 - 371

← 1 2 3 4 5 →