Disposable carbon nanotube modified screen-printed biosensor for amperometric detection of organophosphorus pesticides and nerve agents

被引：228
|
作者：
Lin, YH
Lu, F
Wang, J
机构：
[1] Pacific NW Natl Lab, Richland, WA 99352 USA
[2] New Mexico State Univ, Dept Chem & Biochem, Las Cruces, NM 88003 USA
来源：
ELECTROANALYSIS | 2004年 / 16卷 / 1-2期
关键词：
disposable carbon nanotube modified screen-printed biosensor; amperometric detection; organophosphorous pesticides; nerve agents; acetylcholinesterase/choline oxidase;
D O I：
10.1002/elan.200302933
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A disposable carbon nanotube-based biosensor was successfully developed and applied to the detection of organophosphorus (OP) pesticides and nerve agents. The biosensors using acetycholinesterase (AChE)/choline oxidase (CHO) enzymes provided a high sensitivity, large linear range, and low detection limits for the analysis of OP compounds. Such characteristics may be attributed to the catalytic activity of carbon nanotube to promote the redox reaction of hydrogen peroxide produced during AChE/CHO enzymatic reactions with their substrate, as well as the large surface area of carbon nanotube materials.
引用
收藏
页码：145 / 149
页数：5
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