Temperature-responsive chromatography

被引：51
|
作者：
Kanazawa, H
Matsushima, Y
Okano, T
机构：
[1] Kyoritsu Coll Pharm, Minato Ku, Tokyo 105, Japan
[2] Tokyo Womens Med Coll, Inst Biomed Engn, Shinjuku Ku, Tokyo 162, Japan
来源：
TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 1998年 / 17卷 / 07期
关键词：
temperature-responsive chromatography; poly(N-isopropylacrylamide); stationary phases; thermosensitive;
D O I：
10.1016/S0165-9936(98)00044-2
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
We have developed a new method for HPLC which uses packing materials modified with a temperature-responsive polymer, poly(N-isopropylacrylamide). The surface properties and functions of the stationary phases are controlled by the external temperature. In the proposed chromatographic system, the elution of target substances is controlled by only a small change in the column temperatures. (C) 1998 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：435 / 440
页数：6
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