The effects of different plant extracts on intestinal cestodes and on trematodes

被引:0
|
作者
Abdel-Ghaffar, Fathy [2 ]
Semmler, Margit [2 ]
Al-Rasheid, Khaled A. S. [3 ]
Strassen, Bianca [1 ]
Fischer, Katja [1 ]
Aksu, Gulendem [1 ]
Klimpel, Sven [4 ]
Mehlhorn, Heinz [1 ]
机构
[1] Univ Dusseldorf, Dept Parasitol, D-40225 Dusseldorf, Germany
[2] Cairo Univ, Dept Zool, Giza, Egypt
[3] King Saud Univ, Coll Sci, Dept Zool, Riyadh 11451, Saudi Arabia
[4] Goethe Univ Frankfurt, Biodivers & Climate Change Ctr Bik F, D-60325 Frankfurt, Germany
关键词
DRUGS;
D O I
10.1007/s00436-010-2167-5
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
In the present study, chloroform, aqueous, (polyethylene glycol/propylene carbonate) PEG/PC extracts were made from coconut, onion, garlic, fig, date tree, chicory, ananas, and cistrose. These extracts were tested in vivo and in vitro on their anthelmintic activity against cestodes (Hymenolepis diminuta, H. microstoma, Taenia taeniaeformis) and trematodes (Fasciola hepatica, Echinostoma caproni). In all in vitro tests, the target parasites died. It turned out that the treatment of mice and rats with a combination of onion and coconut extracts (with PEG/PC) eliminated all cestodes from their final hosts. In addition, the same composition was effective against the intestinal fluke E. caproni, but not against the liver fluke F. hepatica in the final host, while both worms were killed in vitro. Inoculation of fluids of coconut eliminated T. taeniaeformis tapeworms from naturally infected cats. This goal was not reached with oil of cistrose.
引用
收藏
页码:979 / 984
页数:6
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