Sequential occurrence of non-small cell and small cell lung cancer with the same EGFR mutation

被引：115

作者：

Morinaga, Ryotaro ^{[1
]}

Okamoto, Isamu ^{[1
]}

Furuta, Kazuyuki ^{[2
]}

Kawano, Yukiko ^{[2
]}

Sekijima, Masaru ^{[2
]}

Dote, Kensaku ^{[3
]}

Satou, Takao ^{[4
]}

Nishio, Kazuto ^{[5
]}

Fukuoka, Masahiro ^{[1
]}

Nakagawa, Kazuhiko ^{[1
]}

机构：

[1] Kinki Univ, Sch Med, Dept Med Oncol, Osaka 5898511, Japan

[2] Mitsubishi Chem Safety Inst Ltd, Kashima Lab, Res Div Adv Technol, Ibaraki, Japan

[3] Kinki Univ, Sch Med, Dept Pathol, Osaka 589, Japan

[4] Kinki Univ, Sch Med, Div Hosp Pathol, Osaka 589, Japan

[5] Kinki Univ, Sch Med, Dept Genome Biol, Osaka 589, Japan

来源：

LUNG CANCER | 2007年 / 58卷 / 03期

关键词：

EGFR mutation; non-small cell lung cancer; small cell lung cancer;

D O I：

10.1016/j.lungcan.2007.05.014

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report a case of small cell lung cancer (SCLC) developing after prolonged treatment (more than 2 years) for primary adenocarcinoma of the lung, and we show that both the SCLC and non-small cell lung cancer (NSCLC) tissues obtained from the same site share the same deletion in exon 19 of EGFR. This case suggests that the activating EGFR mutations may confer the pathogenesis of a subset of SCLC. (c) 2007 Elsevier Ireland Ltd. All rights reserved.

引用

页码：411 / 413

页数：3

共 50 条

[11] EGFR Mutation Testing Practice in Advanced Non-Small Cell Lung Cancer
Jair Bar
Arnold Cyjon
Dov Flex
Hadas Sorotsky
Haim Biran
Julia Dudnik
Nili Peylan-Ramu
Nir Peled
Hovav Nechushtan
Maya Gips
Rivka Katsnelson
Shoshana Keren Rosenberg
Ofer Merimsky
Amir Onn
Maya Gottfried
Lung, 2014, 192 : 759 - 763
[12] Molecular Characterization of Unactionable EGFR Mutation in Non-Small Cell Lung Cancer
Wu, H.
Wang, F.
Wang, P.
Ji, H.
Wang, X.
Gu, D.
Shi, J.
JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (10) : S1147 - S1147
[13] The impact and role of EGFR gene mutation on non-small cell lung cancer
Toyooka, Shinichi
Soh, Junichi
Shigematsu, Hisayuki
Aoe, Motoi
Date, Hiroshi
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2006, 58 (Suppl 1) : S25 - S31
[14] EGFR Mutation Testing Practice in Advanced Non-Small Cell Lung Cancer
Bar, Jair
Cyjon, Arnold
Flex, Dov
Sorotsky, Hadas
Biran, Haim
Dudnik, Julia
Peylan-Ramu, Nili
Peled, Nir
Nechushtan, Hovav
Gips, Maya
Katsnelson, Rivka
Rosenberg, Shoshana Keren
Merimsky, Ofer
Onn, Amir
Gottfried, Maya
LUNG, 2014, 192 (05) : 759 - 763
[15] EGFR mutation testing in non-small cell lung cancer: The Bristol experience
Crosby, Charlene
Smye-Rumsby, T.
Plummeridge, M.
Braybrooke, J.
Dangoor, A.
De Winton, E.
Jankowska, P.
Williams, M.
JOURNAL OF MEDICAL GENETICS, 2011, 48 : S101 - S101
[16] Management of EGFR Mutation-Positive Non-Small Cell Lung Cancer
Lilenbaum, Rogerio A.
Horn, Leora A.
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2016, 14 (5.5): : 672 - 674
[17] EGFR mutation profile in Australian patients with non-small cell lung cancer
Mead, Scott
Lucas, Mark
Pang, Jia-Min
Fellowes, Andrew
Harraway, James
Svobodova, Suzanne
Amanuel, Benhur
Fox, Stephen
PATHOLOGY, 2021, 53 (07) : 933 - 936
[18] A Comparison of Methods for EGFR Mutation Testing in Non-Small Cell Lung Cancer
Young, Elizabeth C.
Owens, Martina M.
Adebiyi, Idowu
Bedenham, Tina
Butler, Rachel
Callaway, Jonathan
Cranston, Treena
Crosby, Charlene
Cree, Ian A.
Dutton, Laura
Faulkes, Catherine
Faulkner, Claire
Howard, Emma
Knight, Julia
Huang, Yuanxue
Lavender, Louise
Lazarou, Lazarus P.
Liu, Hongxiang
Mair, Debbie
Milano, Antonio
Sandell, Stacey
Skinner, Alison
Wallace, Andrew
Williams, Maggie
Spivey, Vicky
Goodall, John
Frampton, Jonathan
Ellard, Sian
DIAGNOSTIC MOLECULAR PATHOLOGY, 2013, 22 (04) : 190 - 195
[19] Concurrent EGFR Mutation and ALK Translocation in Non-Small Cell Lung Cancer
Sweis, Randy F.
Thomas, Sachdev
Bank, Bruce
Fishkin, Paul
Mooney, Colin
Salgia, Ravi
CUREUS, 2016, 8 (02):
[20] EGFR Gene Mutation in Advanced Non-Small Cell Lung Cancer - A Case
Mehmood, Tahir
Irfan, Muhammad
Rashid, Asma
JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (09) : S780 - S780

← 1 2 3 4 5 →