A prospective, randomized, double-blinded, placebo controlled, phase III study to evaluate the efficacy and safety of apatinib plus best supportive care (BSC) compared to placebo plus BSC in patients with advanced or metastatic gastric cancer: The ANGEL study.

被引:5
|
作者
Kang, Yoon-Koo
Boku, Narikazu
Kang, Won Ki
Yoon, Harry H.
Cascinu, Stefano
Al-Batran, Salah-Eddin
Houston, Scott
Park, Cheol Hee
机构
关键词
D O I
10.1200/JCO.2017.35.15_suppl.TPS4138
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
TPS4138
引用
收藏
页数:5
相关论文
共 50 条
  • [31] Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): a randomised, double-blind, placebo-controlled, phase 3 trial
    Li, Jin
    Qin, Shukui
    Xu, Ruihua
    Yau, Thomas C. C.
    Ma, Brigette
    Pan, Hongming
    Xu, Jianming
    Bai, Yuxian
    Chi, Yihebali
    Wang, Liwei
    Yeh, Kun-Huei
    Bi, Feng
    Cheng, Ying
    Le, Anh Tuan
    Lin, Jen-Kou
    Liu, Tianshu
    Ma, Dong
    Kappeler, Christian
    Kalmus, Joachim
    Kim, Tae Won
    LANCET ONCOLOGY, 2015, 16 (06): : 619 - 629
  • [32] A randomized phase III trial comparing sorafenib plus best supportive care (BSC) versus BSC alone in Child-Pugh B patients (pts) with advanced hepatocellular carcinoma (HCC): The BOOST study
    Daniele, Bruno
    Di Maio, Massimo
    Gallo, Ciro
    Gasbarrini, Antonio
    Carteni, Giacomo
    Di Costanzo, Giovan Giuseppe
    Craxi, Antonio
    Cabibbo, Giuseppe
    Bolondi, Luigi
    Granito, Alessandro
    Missale, Gabriele
    Frassoldati, Antonio
    Angelico, Mario
    Roselli, Mario
    Daniele, Gennaro
    Perrone, Francesco
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [33] Phase III randomized study of second line ADI-peg 20 (A) plus best supportive care versus placebo (P) plus best supportive care in patients (pts) with advanced hepatocellular carcinoma (HCC)
    Abou-Alfa, Ghassan K.
    Qin, Shukui
    Ryoo, Baek-Yeol
    Lu, Sheng-Nan
    Yen, Chia-Jui
    Feng, Yin-Hsun
    Lim, Ho Yeong
    Izzo, Francesco
    Colombo, Massimo
    Sarker, Debashis
    Bolondi, Luigi
    Vaccaro, Gina M.
    Harris, William Proctor
    Chen, Zhendong
    Hubner, Richard
    Meyer, Tim
    Bomalaski, John S.
    Lin, ChenChun
    Chao, Yee
    Chen, Li-Tzong
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [34] Phase II randomized trial of autologous tumor lysate dendritic cell vaccine (ADC) plus best supportive care (BSC) compared with BSC, in pre-treated advanced colorectal cancer patients.
    Maurel, Joan
    Caballero-Baos, Miguel
    Mila, Jordi
    Tabera, Jaime
    Varea, Sara
    Vilana, Ramon
    Bianchi, Luis
    Arguis, Pedro
    Pineda, Estela
    Carrera, Gemma
    Cuatrecasas, Miriam
    Paez, David
    Martin-Richard, Marta
    Pages, Mario
    Ramon Ayuso, Juan
    Cid, Joan
    Lozano, Miguel
    Garcia-Albeniz, Xabier
    Castells, Antoni
    Vilella, Ramon
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [35] Nintedanib (N) plus best supportive care (BSC) versus placebo (P) plus BSC for the treatment of patients (pts) with colorectal cancer (CRC) refractory to standard therapies: Subanalysis of the phase III LUME-colon 1 study in pts by prior regorafenib (R) treatment
    Lenz, Heinz-Josef
    Yoshino, Takayuki
    Argiles, Guillem
    Iveson, Timothy
    Sastre, Javier
    Harrison, Mark
    Lim, Howard John
    Tebbutt, Niall C.
    Peeters, Marc
    Satoh, Taroh
    Dittrich, Christian
    Sassi, Mouna
    Loembe, Arsene-Bienvenu
    Van Cutsem, Eric
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (04)
  • [36] Nimotuzumab plus chemoradiotherapy versus placebo plus chemoradiotherapy in patients with locally advanced nasopharyngeal carcinoma (NPC): A prospective, randomized-controlled, double-blinded, multicenter phase III clinical trial.
    Sun, Yan
    Hu, Chaosu
    Lin, Qin
    Gao, Li
    Wang, Jianhua
    Zhu, Xiaodong
    Hao, Junfang
    Lang, Jin Yi
    Wang, Peiguo
    Ye, Ming
    Li, Xia
    Xu, Benhua
    Wu, Rong
    Bai, Chunmei
    You, Qingshan
    Chen, Xiaozhong
    Wang, Jun
    Hu, Desheng
    Wu, Gang
    Pan, Jian-Ji
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
  • [37] Randomized, Placebo-Controlled, Double-Blind, Phase II Study of Axitinib Plus Docetaxel Versus Docetaxel Plus Placebo in Patients With Metastatic Breast Cancer
    Rugo, Hope S.
    Stopeck, Alison T.
    Joy, Anil A.
    Chan, Stephen
    Verma, Shailendra
    Lluch, Anna
    Liau, Katherine F.
    Kim, Sinil
    Bycott, Paul
    Rosbrook, Brad
    Bair, Angel H.
    Soulieres, Denis
    JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (18) : 2459 - 2465
  • [38] Vinorelbine (VNR) plus best supportive care (BSC) vs BSC in the treatment of advanced non-small cell lung cancer (NSCLC) elderly patients (Pts). Results of a phase III randomized trial
    Gridelli, C
    Ianniello, GP
    Maiorino, L
    Brancaccio, L
    Cigolari, S
    Bilancia, D
    Aiello, R
    Zuccarino, L
    Pedicini, T
    Zonato, S
    Pappagallo, GL
    Monfardini, S
    Rossi, A
    Gallo, C
    Perrone, F
    BRITISH JOURNAL OF CANCER, 1998, 78 : 3 - 3
  • [39] Vinorelbine(VNR) plus best supportive care (BSC) vs BSC in the treatment of advanced non-small cell lung cancer (NSCLC) elderly patients (pts). Results of a phase III randomized trial
    Gridelli, C
    Ianniello, GP
    Maiorino, L
    Piantedosi, V
    Cigolari, S
    Manzione, L
    Failla, G
    Zuccarino, L
    Pedicini, T
    Vinante, O
    Castiglione, F
    Clerici, M
    Bearz, A
    Darwish, S
    Rossi, A
    Monfardini, S
    Gallo, C
    Perrone, F
    Frontini, L
    ANNALS OF ONCOLOGY, 1998, 9 : 85 - 85
  • [40] SAFETY, RESOURCE USE, AND QUALITY OF LIFE (QOL) RESULTS FROM PARAMOUNT: A PHASE III STUDY OF MAINTENANCE PEMETREXED PLUS BEST SUPPORTIVE CARE (BSC) VERSUS PLACEBO PLUS BSC IMMEDIATELY FOLLOWING INDUCTION TREATMENT WITH PEMETREXED-CISPLATIN FOR ADVANCED NONSQUAMOUS NON-SMALL CELL LUNG CANCER (NSCLC)
    Gridelli, Cesare
    De Marinis, Filippo
    Pujol, Jean-Louis
    Reck, Martin
    Ramlau, Rodryg
    Parente, Barbara
    Pieters, Thierry
    Middleton, Gary
    Winfree, Katherine
    Melemed, Symantha
    Zimmermann, Annamaria H.
    John, William
    Beyrer, Julie
    Chouaki, Nadia
    Visseren-Grul, Carla
    Paz Ares, Luis
    JOURNAL OF THORACIC ONCOLOGY, 2011, 6 (06) : S323 - S324