Akkermansia muciniphila induces Th17 cells by mediating tryptophan metabolism and exacerbates experimental autoimmune encephalomyelitis (EAE)

被引:0
|
作者
Lin, Xun [1 ]
Tawch, Suzanne [1 ]
Singh, Ankita [1 ]
Morgun, Andriy [2 ]
Shulzhenko, Natalia [2 ]
Kumar, Pawan [1 ]
机构
[1] SUNY Stony Brook, Stony Brook, NY 11794 USA
[2] Oregon State Univ, Corvallis, OR 97331 USA
来源
JOURNAL OF IMMUNOLOGY | 2021年 / 206卷
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Alteration of gut flora ameliorates experimental autoimmune encephalomyelitis in association with contraction of inflammatory Th17 cells
    Yokote, Hiroaki
    Miyake, Sachiko
    Croxford, John
    Mizusawa, Hidehiro
    Yamamura, Tokashi
    CLINICAL IMMUNOLOGY, 2008, 127 : S51 - S51
  • [32] Synthetic Retinoid AM80 Inhibits Th17 Cells and Ameliorates Experimental Autoimmune Encephalomyelitis
    Klemann, Christian
    Raveney, Benjamin J. E.
    Klemann, Anna K.
    Ozawa, Tomoko
    von Hoersten, Stephan
    Shudo, Koichi
    Oki, Shinji
    Yamamura, Takashi
    AMERICAN JOURNAL OF PATHOLOGY, 2009, 174 (06): : 2234 - 2245
  • [33] Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis
    O'Connor, Richard A.
    Prendergast, Catriona T.
    Sabatos, Catherine A.
    Lau, Clement W. Z.
    Leech, Melanie D.
    Wraith, David C.
    Anderton, Stephen M.
    JOURNAL OF IMMUNOLOGY, 2008, 181 (06): : 3750 - 3754
  • [34] NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses
    Gris, Denis
    Ye, Zhengmao
    Iocca, Heather A.
    Wen, Haitao
    Craven, Robin R.
    Gris, Pavel
    Huang, Max
    Schneider, Monika
    Miller, Stephen D.
    Ting, Jenny P. -Y.
    JOURNAL OF IMMUNOLOGY, 2010, 185 (02): : 974 - 981
  • [35] Periplocoside A prevents experimental autoimmune encephalomyelitis by suppressing IL-17 production and inhibits differentiation of Th17 cells
    Zhang, Jing
    Ni, Jia
    Chen, Zhen-hua
    Li, Xin
    Zhang, Ru-jun
    Tang, Wei
    Zhao, Wei-min
    Yang, Yi-fu
    Zuo, Jian-ping
    ACTA PHARMACOLOGICA SINICA, 2009, 30 (08) : 1144 - 1152
  • [36] Periplocoside A prevents experimental autoimmune encephalomyelitis by suppressing IL-17 production and inhibits differentiation of Th17 cells
    Jing Zhang
    Jia Ni
    Zhen-hua Chen
    Xin Li
    Ru-jun Zhang
    Wei Tang
    Wei-min Zhao
    Yi-fu Yang
    Jian-ping Zuo
    Acta Pharmacologica Sinica, 2009, 30 : 1144 - 1152
  • [37] Arctigenin regulates Th1 and Th17 differentiation and ameliorates experimental autoimmune encephalomyelitis
    Zhang, Rongxin
    Li, Wen
    Zhang, Zhihui
    Zhang, Zimu
    Xue, Zhenyi
    Li, Yan
    Zhang, Lijuan
    Da, Yurong
    Yao, Zhi
    JOURNAL OF IMMUNOLOGY, 2015, 194
  • [38] Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis
    Murphy, Aine C.
    Lalor, Stephen J.
    Lynch, Marina A.
    Mills, Kingston H. G.
    BRAIN BEHAVIOR AND IMMUNITY, 2010, 24 (04) : 641 - 651
  • [39] Dehydrodiconiferyl alcohol (DHCA) modulates the differentiation of Th17 and Th1 cells and suppresses experimental autoimmune encephalomyelitis
    Lee, Junghun
    Choi, Jinyong
    Lee, Wonwoo
    Ko, Kyeongryang
    Kim, Sunyoung
    MOLECULAR IMMUNOLOGY, 2015, 68 (02) : 434 - 444
  • [40] Deficiency of the leukocyte integrin inhibitor, Del-1, exacerbates experimental autoimmune encephalomyelitis through increased Th17 cell infiltration
    Lim, Jong-Hyung
    Choi, Eun Young
    Samus, Maryna
    Lee, Seung Hwan
    Kim, Hyesoon
    Hajishengallis, George
    Chavakis, Triantafyllos
    JOURNAL OF IMMUNOLOGY, 2013, 190