Adherence to antibiotherapy guidelines for acute community-acquired pneumonia in adults, in a teaching hospital

被引:1
|
作者
Martinez, J. -S. [1 ]
Le Falher, G. [1 ]
Corne, P. [2 ]
Bourdin, A. [3 ]
Lequellec, A. [4 ]
Delabre, J. -P. [5 ]
Makinson, A. [1 ]
Hansel, S. [6 ]
Reynes, J. [1 ]
Le Moing, V. [1 ]
机构
[1] Hop Gui de Chauliac, Serv Malad Infect & Trop, F-34295 Montpellier 5, France
[2] Hop Gui de Chauliac, Serv Reanimat Med Assistance Resp, F-34295 Montpellier 5, France
[3] Hop Arnaud deVilleneuve, Serv Malad Resp, F-34295 Montpellier 5, France
[4] Hop St Eloi, Serv Med Interne, F-34295 Montpellier 5, France
[5] Hop Lapeyronie, Serv Reanimat Metabol, F-34295 Montpellier 5, France
[6] Hop Lapeyronie Arnaud de Villeneuve, Lab Pharm Clin, F-34295 Montpellier 5, France
来源
MEDECINE ET MALADIES INFECTIEUSES | 2010年 / 40卷 / 08期
关键词
Practice assessment; Antibiotics; Community-acquired pneumonia; ANTIMICROBIAL THERAPY; ANTIBIOTICS; PRESCRIPTION; INFECTIONS; MANAGEMENT; RESISTANCE; DIAGNOSIS; PROGRAM; IMPACT;
D O I
10.1016/j.medmal.2010.01.009
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Objective. - The authors had for aim to assess the conformity of antibiotic prescription with guidelines, for the management of community-acquired pneumonia, in a French University Hospital. Design. - This prospective study included adults patients hospitalized for pneumonia over a period of six months. The attending physician estimated the severity of pneumonia. The adequacy to guidelines focused on: first antibiotic choice and prescription modality, antibiotic choice in case of treatment modification at 48 to 72 hours, and duration of antibiotherapy. Results. - A hundred and nine cases of pneumonia were included in 106 patients. The mean age was 66 years, the mortality rate was 17%. Bacterial documentation was recorded in 40.4% of cases. The first antibiotics used were in accordance with guidelines in 52.3% of cases. The non conformity rate was minor in 55.8% of cases. Antibiotherapies putting the patient at risk were used in less than 10% of the cases. The rate of antibiotic modification at 48 to 72 hours was 46.8%, primarily for bacteriological purposes (35.3%) or initial treatment failure (27.4%). The treatment duration was inappropriate in 52.7% of cases and generally too long in case of non conformity. Conclusion. - It seems important to support guideline information, training of prescribers, and to consult an antibiotic expert. (C) 2010 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:468 / 475
页数:8
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