Highly active and enantioselective copper-catalyzed conjugate addition of diethylzinc to cyclohexenone using sugar derivative diphosphites

被引：41
|
作者：
Pàmies, O [1 ]
Diéguez, M [1 ]
Net, G [1 ]
Ruiz, A [1 ]
Claver, C [1 ]
机构：
[1] Univ Rovira & Virgili, Dept Quim Fis & Inorgan, Tarragona 43005, Spain
来源：
TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 21期
关键词：
D O I：
10.1016/S0957-4166(00)00430-4
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
High enantioselectivity combined with unprecedented high catalytic activity (81% ee and TOF approximate to 1200 h(-1)) are achieved in the copper-catalyzed 1,4-addition of diethylzinc to 2-cyclohexenone with new C-1-chiral diphosphites derived from the readily available D-(+)-xylose. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：4377 / 4383
页数：7
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