Diabetic lipemia with maturity-onset diabetes of the young

被引：6

作者：

KadotaShinozaki, A ^{[1
]}

Nakamura, T ^{[1
]}

Hidaka, H ^{[1
]}

Kojima, H ^{[1
]}

Yasuda, H ^{[1
]}

Kashiwagi, A ^{[1
]}

Kikkawa, R ^{[1
]}

机构：

[1] SHIGA UNIV MED SCI,DEPT MED 3,OTSU,SHIGA 52021,JAPAN

来源：

INTERNAL MEDICINE | 1997年 / 36卷 / 08期

关键词：

lipoprotein lipase; type V hyperlipidemia; diabetes mellitus; ketoacidosis;

D O I：

10.2169/internalmedicine.36.571

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 19-year-old woman with diabetic lipemia and maturity-onset diabetes of the young (MODY) is reported. Though her insulin secretory activity was preserved, she fell into mild diabetic ketoacidosis (DKA) and showed type V hyperlipidemia. Post-heparin plasma activity of lipoprotein lipase (LPL) was decreased even 10 days after initiating insulin injection but not deficient. The abnormalities in lipid metabolism were improved by long-term insulin treatment. Though the contribution of the genetic background to the lipid abnormalities is not clear, the characteristics of MODY in this patient including insulin secretory capacity under stress conditions such as DKA might play a role in the development of diabetic lipemia.

引用

页码：571 / 574

页数：4

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