FREQUENCY AND CHARACTERISTICS OF INTRAOCULAR INFLAMMATION AFTER AFLIBERCEPT INJECTION

被引：20
|
作者：
Fine, Howard F. [1 ]
Roth, Daniel B. [1 ]
Shah, Sumit P. [1 ]
Haque, Tahia [1 ]
Wheatley, Matthew [1 ]
机构：
[1] Rutgers Robert Wood Johnson Med Sch, Dept Ophthalmol, New Brunswick, NJ 08901 USA
来源：
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | 2015年 / 35卷 / 04期
关键词：
aflibercept; endophthalmitis; intravitreal injection; noninfectious endophthalmitis; uveitis; INTRAVITREAL INJECTION; MACULAR DEGENERATION; RANIBIZUMAB INJECTIONS; BEVACIZUMAB; SAFETY; VERTEPORFIN;
D O I：
10.1097/IAE.0000000000000398
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose: To report the frequency and characteristics of intraocular inflammation after intravitreal aflibercept injection. Methods: A single-center retrospective study was performed in patients who received intravitreal aflibercept from November 2011 through June 2013. Results: There were 28 cases of intraocular inflammation after a total of 5,905 aflibercept injections among 1,660 patients. The mean baseline acuity was 20/57, which decreased to 20/179 at diagnosis (P < 0.0001) but recovered to 20/59 at Month 1, 20/57 at Month 3, and 20/52 at Month 6 (P = not significant). Vitreous culture and injection of antibiotics were performed in eight cases, and all were culture negative; the remainder received only topical corticosteroids. Conclusion: The frequency of inflammation after aflibercept was 0.47% per injection. Visual acuity and inflammation returned to baseline within 1 month in most cases with topical corticosteroid treatment.
引用
收藏
页码：681 / 686
页数：6
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