Age-related muscle dysfunction

被引：153
|
作者：
Thompson, LaDora V. [1 ]
机构：
[1] Univ Minnesota, Dept Phys Med & Rehabil, Minneapolis, MN 55455 USA
来源：
EXPERIMENTAL GERONTOLOGY | 2009年 / 44卷 / 1-2期
关键词：
Actin; Myosin; Aged muscle; Enzymatic activity; oxidative modifications; TANDEM MASS-SPECTROMETRY; RAT SKELETAL-MUSCLE; MYOSIN ATPASE ACTIVITY; GLYCATION END-PRODUCT; IN-VIVO; PROTEOMIC IDENTIFICATION; PROTEIN NITRATION; DEPENDENT ACCUMULATION; CONTRACTILE PROPERTIES; FORCE GENERATION;
D O I：
10.1016/j.exger.2008.05.003
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Aging is associated with a progressive decline of muscle mass, strength, and quality, a condition described as sarcopenia. Despite the significance of skeletal muscle atrophy, the mechanisms responsible for the deterioration of muscle performance are only partially understood. The purpose of this review is to highlight cellular, molecular, and biochemical changes that contribute to age-related muscle dysfunction. (c) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码：106 / 111
页数：6
相关论文
共 50 条
  • [31] Age-Related Lymphatic Dysfunction in Melanoma Patients
    W. Charles Conway
    Mark B. Faries
    Michael B. Nicholl
    Alicia M. Terando
    Edwin C. Glass
    MyungShin Sim
    Donald L. Morton
    Annals of Surgical Oncology, 2009, 16 : 1548 - 1552
  • [32] Telomere dysfunction in ageing and age-related diseases
    Francesca Rossiello
    Diana Jurk
    João F. Passos
    Fabrizio d’Adda di Fagagna
    Nature Cell Biology, 2022, 24 : 135 - 147
  • [33] Mitochondrial Aging and Age-Related Dysfunction of Mitochondria
    Chistiakov, Dimitry A.
    Sobenin, Igor A.
    Revin, Victor V.
    Orekhov, Alexander N.
    Bobryshev, Yuri V.
    BIOMED RESEARCH INTERNATIONAL, 2014, 2014
  • [34] The role of mitochondrial dysfunction in age-related diseases
    Lane, Rebecca K.
    Hilsabeck, Tyler
    Rea, Shane L.
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2015, 1847 (11): : 1387 - 1400
  • [35] Microcirculation Dysfunction in Age-related Cognitive Impairment
    Chen Xi-Xi
    Su Tao
    PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2015, 42 (12) : 1077 - 1083
  • [36] Age-Related Lymphatic Dysfunction in Melanoma Patients
    Conway, W. Charles
    Faries, Mark B.
    Nicholl, Michael B.
    Terando, Alicia M.
    Glass, Edwin C.
    Sim, MyungShin
    Morton, Donald L.
    ANNALS OF SURGICAL ONCOLOGY, 2009, 16 (06) : 1548 - 1552
  • [37] Skeletal Muscle Function Deficit: A New Terminology to Embrace the Evolving Concepts of Sarcopenia and Age-Related Muscle Dysfunction
    Correa-de-Araujo, Rosaly
    Hadley, Evan
    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2014, 69 (05): : 591 - 594
  • [38] Are markers of inflammation and endothelial dysfunction related to age-related maculopathy?
    Klein, R
    Klein, BEK
    Knudtson, MD
    Shankar, A
    Wong, TY
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2005, 46
  • [39] Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration
    A. Sahu
    H. Mamiya
    S. N. Shinde
    A. Cheikhi
    L. L. Winter
    N. V. Vo
    D. Stolz
    V. Roginskaya
    W. Y. Tang
    C. St. Croix
    L. H. Sanders
    M. Franti
    B. Van Houten
    T. A. Rando
    A. Barchowsky
    F. Ambrosio
    Nature Communications, 9
  • [40] Age-Related Skeletal Muscle Dysfunction Is Aggravated by Obesity: An Investigation of Contractile Function, Implications and Treatment
    Tallis, Jason
    Shelley, Sharn
    Degens, Hans
    Hill, Cameron
    BIOMOLECULES, 2021, 11 (03) : 1 - 31
12345