Origins of the double asymmetric induction on proline-catalyzed aldol reactions

被引：38

作者：

Calderon, Felix ^{[1
]}

Doyagueez, Elisa G. ^{[1
]}

Cheong, Paul Ha-Yeon ^{[2
]}

Fernandez-Mayoralas, Alfonso ^{[1
]}

Houk, K. N. ^{[2
]}

机构：

[1] CSIC, Inst Quim Organ Gen, E-28006 Madrid, Spain

[2] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2008年 / 73卷 / 20期

关键词：

D O I：

10.1021/jo800934b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Computational studies to elucidate the origin of the double asymmetric induction on proline-catalyzed aldol reaction have been performed using HF/6-31G(d) calculations. The computed transition structures explain the experimental data obtained.

引用

页码：7916 / 7920

页数：5

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