Indole-3-carbinol (I3C) and gemcitabine as potential combinatorial therapy in pancreatic cancer

被引:0
|
作者
Lyn-Cook, Beverly [1 ]
Mohammed, Sulma [2 ,3 ]
Word, Beverly [1 ]
Hammons, George [1 ]
机构
[1] Natl Ctr Toxicol Res, Jefferson, AR 72079 USA
[2] Purdue Univ, W Lafayette, IN 47907 USA
[3] Purdue Univ, Canc Res Ctr, W Lafayette, IN 47907 USA
关键词
D O I
10.1158/1538-7445.AM2011-2556
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2556
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Gender Differences in Gemcitabine (Gemzar) Efficacy in Cancer Cells: Effect of Indole-3-Carbinol
    Lyn-Cook, Beverly D.
    Mohammed, Sulma I.
    Davis, Cornelius
    Word, Beverly
    Haefele, Aaron
    Wang, Honggang
    Hammons, George
    ANTICANCER RESEARCH, 2010, 30 (12) : 4907 - 4913
  • [32] INDOLE-3-CARBINOL - RESPONSE
    MICHNOVICZ, JJ
    BRADLOW, HL
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1992, 84 (15): : 1211 - 1212
  • [33] Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells
    Sreenivasa R Chinni
    Yiwei Li
    Sunil Upadhyay
    Prathima K Koppolu
    Fazlul H Sarkar
    Oncogene, 2001, 20 : 2927 - 2936
  • [34] Diindolylmethane (DIM), formed spontaneously from Indole-3-carbinol (I3C), is the dominant anti-proliferative indole in cell culture media after adding I3C.
    Zeligs, Michael A.
    Bradlow, H. Leon
    CANCER RESEARCH, 2006, 66 (08)
  • [35] Chemosensitivity of indole-3-carbinol via downregulation of microRNA-21 in gemcitabine-resistant pancreatic cancer cells
    Kim, H. R.
    Jang, S. E.
    Beik, W. H.
    Lee, S. H.
    Hwang, J-H
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2011, 26 : 232 - 232
  • [36] INDOLE-3-CARBINOL AND EPIGALLOCATECHIN-3-GALLATE IN COMBINATION THERAPY OF OVARIAN CANCER
    Ashrafyan, L. A.
    Antonova, I. B.
    Aleshikova, O. I.
    Gerfanova, E. V.
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2015, 25 (09) : 432 - 432
  • [37] Indole-3-carbinol (I3C) reduces apoptosis and improves neurological function after cerebral ischemia–reperfusion injury by modulating microglia inflammation
    Long Peng
    Xingjia Zhu
    Chenxing Wang
    Qiaoji Jiang
    Shian Yu
    Gaochao Song
    Qianqian Liu
    Peipei Gong
    Scientific Reports, 14
  • [38] Indole-3-Carbinol (I3C) Protects the Heart From Ischemia/Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Cellular Apoptosis in Mice
    Li, Qi
    Xia, Boyu
    Wu, Jingjing
    Yuan, Xiaomei
    Lu, Xu
    Huang, Chao
    Gu, Hongcheng
    Zheng, Koulong
    You, Qingsheng
    Liu, Kun
    FRONTIERS IN PHARMACOLOGY, 2022, 13
  • [39] OSU-A9, an indole-3-carbinol derivative, is a new potential antitumor agent for advanced pancreatic cancer
    Tsai, Wan-Chi
    Tsai, Chen-Hsun
    Weng, Jing-Ru
    Kulp, Samuel
    Chen, Ching-Shih
    CANCER RESEARCH, 2009, 69
  • [40] Indole-3-carbinol (I3C) increases the expression of UDP-glucuronsyl-transferases in estrogen receptor negative and positive breast cancer cells: role of DNA methylation
    Lyn-Cook, Beverly
    Edwards, Timesha
    Starlard-Davenport, Athena
    Word, Beverly
    Hammons, George
    CANCER RESEARCH, 2009, 69