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Bone Mineral Density Increases in HIV-Infected Children Treated With Long-term Combination Antiretroviral Therapy
被引:13
|作者:
Bunders, Madeleine J.
[1
]
Frinking, Olivier
[1
]
Scherpbier, Henriette J.
[1
]
van Arnhem, Lotus A.
[1
]
van Eck-Smit, Berthe L.
[2
]
Kuijpers, Taco W.
[1
]
Zwinderman, Aeilko H.
[3
]
Reiss, Peter
[4
,5
]
Pajkrt, Dasja
[1
]
机构:
[1] Emma Children Hosp, Dept Paediat Immunol Haematol & Infect Dis, Amsterdam, Netherlands
[2] Univ Amsterdam, Acad Med Ctr, Dept Nucl Med, NL-1105 AZ Amsterdam, Netherlands
[3] Univ Amsterdam, Acad Med Ctr, Dept Clin Epidemiol Biostat & Bioinformat, NL-1105 AZ Amsterdam, Netherlands
[4] Univ Amsterdam, Acad Med Ctr, Ctr Infect & Immun, Div Infect Dis, NL-1105 AZ Amsterdam, Netherlands
[5] Univ Amsterdam, Acad Med Ctr, Dept Global Hlth, Amsterdam Inst Global Hlth & Dev, NL-1105 AZ Amsterdam, Netherlands
关键词:
bone mineral density;
pediatric HIV;
cART;
TENOFOVIR DISOPROXIL FUMARATE;
AIDS;
D O I:
10.1093/cid/cis917
中图分类号:
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号:
100102 ;
摘要:
The long-term treatment of human immunodeficiency virus (HIV)-infected children with combination antiretroviral therapy (cART) requires assessment of potential adverse effects, such as osteoporosis. Longitudinal data on bone mineral density (BMD) in HIV-infected children showed that cumulative treatment with cART had a positive impact on BMD over time.
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页码:583 / 586
页数:4
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