Caenorhabditis elegans reveals novel Pseudomonas aeruginosa virulence mechanism

被引:26
|
作者
Utari, Putri Dwi [1 ]
Quax, Wim J. [1 ]
机构
[1] Univ Groningen, Dept Pharmaceut Biol, NL-9713 AV Groningen, Netherlands
关键词
PAO1;
D O I
10.1016/j.tim.2013.04.006
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The susceptibility of Caenorhabditis elegans to different virulent phenotypes of Pseudomonas aeruginosa makes the worms an excellent model for studying host-pathogen interactions. Including the recently described liquid killing, five different killing assays are now available offering superb possibilities for performing high-throughput screens for novel antibiotics using a whole-body infection system.
引用
收藏
页码:315 / 316
页数:2
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