Case Report: Cutaneous Leishmaniasis in a Rheumatoid Arthritis Patient Receiving Methotrexate

被引：1

作者：

Amato, Valdir Sabbaga ^{[1
,2
]}

de Souza, Regina Maia ^{[1
]}

Franco, Lucas Augusto Moyses ^{[1
,2
]}

Martins, Roberta Cristina Ruedas ^{[1
]}

da Silva, Camila Alves Maia ^{[1
]}

Emori, Christini Takemi ^{[1
,2
]}

Celeste, Beatriz Julieta ^{[2
,3
]}

Castanheira, Gabriel Victor ^{[1
,2
]}

Tuon, Felipe Francisco ^{[3
,4
,5
]}

机构：

[1] Univ Sao Paulo, Inst Med Trop Sao Paulo, Lab Parasitol, Sao Paulo, SP, Brazil

[2] Univ Sao Paulo, Fac Med, Dept Molestias Infecciosas & Parasitarias, Sao Paulo, SP, Brazil

[3] Univ Sao Paulo, Lab Soroepidemiol, Inst Med Trop Sao Paulo, Sao Paulo, SP, Brazil

[4] Pontificia Univ Catol Parana, Lab Emerging Infect Dis, Curitiba, PR, Brazil

[5] Rua Imaculada Conceicao 1155, BR-80215901 Curitiba, PR, Brazil

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2022年 / 107卷 / 04期

关键词：

VISCERAL LEISHMANIASIS; VIANNIA DNA; DIAGNOSIS; BLOOD;

D O I：

10.4269/ajtmh.22-0180

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The immunosuppressive effect of methotrexate has rarely been associated with reactivation of cutaneous leishmaniasis. Here we present a case of a cutaneous leishmaniasis patient with atypical clinical symptoms without splenomegaly but with cutaneous manifestations after treatment of rheumatoid arthritis with methotrexate and blood recovery of the parasite. Next-generation sequencing was used to identify Leishmania infantum chagasi in the patient's blood sample.

引用

页码：785 / 788

页数：4

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