Prevention of peroxynitrite-induced oxidation and nitration reactions by ellagic acid

被引：12
|
作者：
Ippoushi, Katsunari [1 ]
Takeuchi, Atsuko [1 ]
Azuma, Keiko [1 ]
机构：
[1] Natl Agr & Food Res Org, Natl Inst Vegetable & Tea Sci, Tsu, Mie 5142392, Japan
来源：
FOOD CHEMISTRY | 2009年 / 112卷 / 01期
关键词：
ellagic acid; peroxynitrite; antioxidative effect; IN-VITRO; TYROSINE NITRATION; DNA-DAMAGE; INHIBITION; NITROGEN; SYSTEM; IMPACT;
D O I：
10.1016/j.foodchem.2008.05.057
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Four benzoic acid derivatives and three phenylpropanoids were tested for their ability to suppress oxidation of dichlorodihydrofluorescein (DCDHF) induced by 3-morpholinosydnonimine (SIN-1, a peroxynitrite donor). Ellagic acid was found to potently inhibit this oxidation and to inhibit oxidation of DCDHF induced by peroxynitrite itself. Moreover, this compound prevented peroxynitrite-induced oxidative single strand breaks in pTZ 18U plasmid DNA and nitration of tyrosyl residues in bovine serum albumin. These results show that ellagic acid protects biomolecules against oxidative and nitrative damage induced by peroxynitrite in vitro. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：185 / 188
页数：4
相关论文
共 50 条
  • [1] Prevention of peroxynitrite-induced nitration and oxidation by nitroxides
    Sadowska-Bartosz, Izabela
    Bartosz, Grzegorz
    FREE RADICAL BIOLOGY AND MEDICINE, 2015, 86 : S35 - S35
  • [2] Nitroxides protect against peroxynitrite-induced nitration and oxidation
    Sadowska-Bartosz, Izabela
    Gajewska, Agnieszka
    Skolimowski, Janusz
    Szewczyk, Rafal
    Bartosz, Grzegorz
    FREE RADICAL BIOLOGY AND MEDICINE, 2015, 89 : 1165 - 1175
  • [3] Mechanism of inhibition of peroxynitrite-induced oxidation and nitration by [6]-gingerol
    Ippoushi, K
    Ito, H
    Horie, H
    Azuma, K
    PLANTA MEDICA, 2005, 71 (06) : 563 - 566
  • [4] Peroxynitrite-induced tyrosine nitration and phosphorylation in human platelets
    Mondoro, TH
    Shafer, BC
    Vostal, JG
    FREE RADICAL BIOLOGY AND MEDICINE, 1997, 22 (06) : 1055 - 1063
  • [5] Hydroxyguanidines inhibit peroxynitrite-induced oxidation
    Southan, GJ
    Salzman, AL
    Szabó, C
    FREE RADICAL BIOLOGY AND MEDICINE, 1998, 25 (08) : 914 - 925
  • [6] Peroxynitrite-induced nitration & oxidation in cytoskeletal instability & loss of intestinal epithelial barrier function (BF).
    Banan, A
    Choudhary, S
    Zhang, Y
    Keshavarzian, A
    GASTROENTEROLOGY, 2000, 118 (04) : A803 - A803
  • [7] PEROXYNITRITE-INDUCED TYROSINE NITRATION MEDIATES DECREASED POLYMERIZATION OF ACTION
    SELDEN, LA
    GERSHMAN, LC
    ESTES, JE
    FERRO, TJ
    JOHNSON, A
    MOLECULAR BIOLOGY OF THE CELL, 1995, 6 : 113 - 113
  • [8] Peroxynitrite-induced inhibition and nitration of cardiac myofibrillar creatine kinase
    Mihm, MJ
    Bauer, JA
    BIOCHIMIE, 2002, 84 (10) : 1013 - 1019
  • [9] Peroxynitrite-induced tyrosine nitration and inhibition of protein kinase C
    Knapp, LT
    Kanterewicz, BI
    Hayes, EL
    Klann, E
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 286 (04) : 764 - 770
  • [10] Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: Structures and mechanisms of product formation
    Niles, JC
    Wishnok, JS
    Tannenbaum, SR
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2006, 14 (02): : 109 - 121
12345