One-pot assembly of 3,5-bis(1H-pyrrol-2-yl)-4H-1,2,4-triazol-4-amines from pyrrolecarbo-nitriles and hydrazine

被引：1
|
作者：
Glotova, T. E. [1 ]
Shabalin, D. A. [1 ]
Dvorko, M. Yu. [1 ]
Ushakov, I. A. [1 ]
Schmidt, E. Yu. [1 ]
Ivanov, A. V. [1 ]
Mikhaleva, A. I. [1 ]
Trofimov, B. A. [1 ]
机构：
[1] Russian Acad Sci, Siberian Branch, AE Favorsky Irkutsk Inst Chem, Irkutsk 664033, Russia
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2013年 / 49卷 / 04期
关键词：
3,5-bis(1H-pyrrol-2-yl)-4H-1,2,4-triazol-4-amines; hydrazine hydrate; 1H-pyrrole-2-carbonitriles; ANTIMICROBIAL ACTIVITY; DERIVATIVES; CHEMISTRY;
D O I：
10.1007/s10593-013-1282-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reaction of pyrrole-2-carbonitriles with hydrazine hydrate in the presence of hydrazine dihydrochloride (ethylene glycol, 130-132A degrees D, 1-2 h, argon atmosphere) affords the hitherto unknown 3,5-bis(1H-pyrrol-2-yl)-4H-1,2,4-triazol-4-amines in up to 86% yield.
引用
收藏
页码：561 / 565
页数：5
相关论文
共 50 条
  • [21] 3,5-Bis[5-(thiazol-2-yl)thien-2-yl]-4H-1,2,6-thiadiazin-4-one
    Kalogirou, Andreas S.
    Koutentis, Panayiotis A.
    MOLBANK, 2019, (01)
  • [22] Bis{4-[(4H-1,2,4-triazol-4-yl)iminomethyl]pyridinium} diaquapentanitratocerate(III)
    Sun, Qiaozhen
    Zheng, Feng
    Sun, Xiaodan
    Wang, Wei
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : M124 - U1245
  • [23] 1-acetonyl-4-(3,5-diethyl-4H-1,2,4-triazol-4-yl)-3-(2-thienylmethyl)-1H-1,2,4-triazol-5(4H)-one
    Ustabas, Resat
    Coruh, Ufuk
    Sancak, Kemal
    Dugdu, Esra
    Vazquez-Lopez, Ezequiel M.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 : O4265 - O4267
  • [24] REACTION OF 2,5-BIS(TRIFLUOROMETHYL)-1,3,4-OXADIAZOLE WITH PRIMARY AMINES - SYNTHESIS OF 4-SUBSTITUTED-3,5-BIS(TRIFLUOROMETHYL)-4H-1,2,4-TRIAZOLES
    REITZ, DB
    FINKES, MJ
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1989, 26 (01) : 225 - 230
  • [25] 4-(p-bromophenyl)-3,5-bis(2-pyridyl)-4H-1,2,4-triazole
    Chen, W
    Wang, ZX
    Jian, FF
    Bai, ZP
    You, XZ
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1998, 54 : 851 - 852
  • [26] 4-[4-(dimethylamino)benzylideneamino]-3,5-bis(2-pyridyl)-4H-1,2,4-triazole
    Bruno, G
    Nicoló, F
    Puntoriero, F
    Giuffrida, G
    Ricevuto, V
    Rosace, G
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 2003, 59 : O390 - O391
  • [27] 4-(p-Methoxyphenyl)-3,5-bis (2-pyridyl)-4H-1,2,4-triazole
    Fun, HK
    Chinnakali, K
    Shao, SC
    Zhu, DR
    You, XZ
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1999, 55 : 770 - 772
  • [28] 4-(p-Bromophenyl)-3,5-bis(2-pyridyl)-4H-1,2,4-triazole
    Acta Crystallogr Sect C Cryst Struct Commun, pt 6 (851-852):
  • [29] 1-(Benzoylmethyl)-4-(3,5-dimethyl-4H-1,2,4-triazol-4-yl)-3-(2-thienylmethyl)-1H-1,2,4-triazol-5(4H)-one
    Sancak, K
    Çoruh, UC
    Ünver, Y
    Vázquez-López, EM
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : O1785 - O1787
  • [30] A quantum-chemical investigation on 3-(4H-1,2,4-triazol-4-yl)-1H-1,2,4-Triazole
    Abbasoglu, R
    Saltek, N
    Ikizler, AA
    TURKISH JOURNAL OF CHEMISTRY, 1997, 21 (02): : 144 - 150
12345