One-pot assembly of 3,5-bis(1H-pyrrol-2-yl)-4H-1,2,4-triazol-4-amines from pyrrolecarbo-nitriles and hydrazine

被引：1
|
作者：
Glotova, T. E. [1 ]
Shabalin, D. A. [1 ]
Dvorko, M. Yu. [1 ]
Ushakov, I. A. [1 ]
Schmidt, E. Yu. [1 ]
Ivanov, A. V. [1 ]
Mikhaleva, A. I. [1 ]
Trofimov, B. A. [1 ]
机构：
[1] Russian Acad Sci, Siberian Branch, AE Favorsky Irkutsk Inst Chem, Irkutsk 664033, Russia
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2013年 / 49卷 / 04期
关键词：
3,5-bis(1H-pyrrol-2-yl)-4H-1,2,4-triazol-4-amines; hydrazine hydrate; 1H-pyrrole-2-carbonitriles; ANTIMICROBIAL ACTIVITY; DERIVATIVES; CHEMISTRY;
D O I：
10.1007/s10593-013-1282-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reaction of pyrrole-2-carbonitriles with hydrazine hydrate in the presence of hydrazine dihydrochloride (ethylene glycol, 130-132A degrees D, 1-2 h, argon atmosphere) affords the hitherto unknown 3,5-bis(1H-pyrrol-2-yl)-4H-1,2,4-triazol-4-amines in up to 86% yield.
引用
收藏
页码：561 / 565
页数：5
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