Triterpenoid Saponins from Rubus ellipticus var. obcordatus

被引：69
|
作者：
Li, Wei [1 ]
Fu, Hongwei [1 ,2 ]
Bai, Hong [3 ]
Sasaki, Tatsunori [1 ]
Kato, Hiroyoshi [1 ]
Koike, Kazuo [1 ]
机构：
[1] Toho Univ, Fac Pharmaceut Sci, Chiba 2748510, Japan
[2] Zhejiang Univ, Dept Biomed Engn, Zhejiang Prov Key Lab Chinese Med Screening Explo, Key Lab Biomed Engn Minist Educ, Hangzhou 310027, Peoples R China
[3] Shandong Acad Med Sci, Inst Mat Med, Jinan 250062, Peoples R China
来源：
JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 10期
关键词：
PENTACYCLIC TRITERPENOIDS; STEM BARK; GLUCOSIDES; LEAVES; PLANTS;
D O I：
10.1021/np900237a
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Ten new triterpenoid saponins (1-10), named rubusides A-J, and 21 known saponins (11-31) were isolated from the roots of Rubus ellipticus var. obcordatus. The structures of 1-10 were established on the basis of spectroscopic analyses, mainly NMR and MS, and chemical degradations. The compounds demonstrated inhibitory activities against (X-glucosidase with IC(50) values in the range 0.65-3.09 mM.
引用
收藏
页码：1755 / 1760
页数：6
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