Synthesis of cryptoporic acid A methyl ester

被引:12
|
作者
Tori, M [1 ]
Hamada, N [1 ]
Sono, M [1 ]
Sono, Y [1 ]
Ishikawa, M [1 ]
Nakashima, K [1 ]
Hashimoto, T [1 ]
Asakawa, Y [1 ]
机构
[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Yamashiro, Tokushima 7708514, Japan
关键词
addition reactions; carboxylic acids and derivatives; enolates; terpenes and terpenoids;
D O I
10.1016/S0040-4039(00)00317-8
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An anti-tumor promoter, cryptoporic acid A methyl ester, has been synthesized by 1,4-addition of the enolate derived from the methoxycarbonylmethyl ether of albicanol to methyl maleate or fumarate as well as three other diastereoisomers. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:3099 / 3102
页数:4
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