Parkinson's disease: an update on pathogenesis and treatment

被引：28
|
作者：
Foltynie, Tom [1 ,2 ]
Kahan, Joshua [2 ]
机构：
[1] Natl Hosp Neurol & Neurosurg, Box 146,Queen Sq, London WC1N 3BG, England
[2] UCL Inst Neurol, Sobell Dept Motor Neurosci, London WC1N 3BG, England
来源：
JOURNAL OF NEUROLOGY | 2013年 / 260卷 / 05期
关键词：
Parkinson's disease; Pathogenesis; Treatment; Update; ALPHA-SYNUCLEIN; NEUROTROPHIC FACTOR; SUBSTANTIA-NIGRA; CONTROLLED-TRIAL; DOPAMINERGIC-NEURONS; RODENT MODELS; GENE-THERAPY; COMPLEX-I; GLUCOCEREBROSIDASE; BRAIN;
D O I：
10.1007/s00415-013-6915-1
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The Parkinson's disease research field is a rapidly moving one, as many of the relevant processes underlying PD neurodegeneration are being deciphered, enabling novel approaches to treatment to be assessed both in the laboratory and in the clinic. This review aims to highlight the most relevant updates in the PD field, with emphasis on research that may help lead towards an improvement in the treatment of this condition.
引用
收藏
页码：1433 / 1440
页数：8
相关论文
共 50 条
  • [31] Pain in Parkinson's disease: new concepts in pathogenesis and treatment
    Rukavin, Katarina
    Leta, Valentina
    Sportelli, Carolina
    Buhidma, Yazead
    Duty, Susan
    Malcangio, Marzia
    Chaudhuri, Kallol Ray
    CURRENT OPINION IN NEUROLOGY, 2019, 32 (04) : 579 - 588
  • [32] Update on Parkinson's disease
    Young, R
    AMERICAN FAMILY PHYSICIAN, 1999, 59 (08) : 2155 - 2167
  • [33] Ubiquitin phosphorylation in Parkinson's disease: Implications for pathogenesis and treatment
    Chin, Lih-Shen
    Li, Lian
    TRANSLATIONAL NEURODEGENERATION, 2016, 5
  • [34] Stem cell treatment for Parkinson's disease: an update for 2005
    Snyder, BJ
    Olanow, CW
    CURRENT OPINION IN NEUROLOGY, 2005, 18 (04) : 376 - 385
  • [35] An update on the recognition and treatment of autonomic symptoms in Parkinson's disease
    Jost, Wolfgang H.
    EXPERT REVIEW OF NEUROTHERAPEUTICS, 2017, 17 (08) : 791 - 799
  • [36] Update on the treatment of Parkinson's disease psychosis: role of pimavanserin
    Combs, Brianna L.
    Cox, Arthur G.
    NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2017, 13 : 737 - 744
  • [37] Glucocerebrosidase in the pathogenesis and treatment of Parkinson disease
    Schapira, Anthony H. V.
    Gegg, Matthew E.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (09) : 3214 - 3215
  • [38] An update on the diagnosis and treatment of Parkinson disease
    Rizek, Philippe
    Kumar, Niraj
    Jog, Mandar S.
    CANADIAN MEDICAL ASSOCIATION JOURNAL, 2016, 188 (16) : 1157 - 1165
  • [39] Behcet's disease:: An update on the pathogenesis
    Gül, A
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2001, 19 (05) : S6 - S12
  • [40] Castleman's disease Update on pathogenesis
    Al-Maghrabi, Jaudah A.
    SAUDI MEDICAL JOURNAL, 2011, 32 (05) : 451 - 458
12345