Parkinson's disease: an update on pathogenesis and treatment

被引：28
|
作者：
Foltynie, Tom [1 ,2 ]
Kahan, Joshua [2 ]
机构：
[1] Natl Hosp Neurol & Neurosurg, Box 146,Queen Sq, London WC1N 3BG, England
[2] UCL Inst Neurol, Sobell Dept Motor Neurosci, London WC1N 3BG, England
来源：
JOURNAL OF NEUROLOGY | 2013年 / 260卷 / 05期
关键词：
Parkinson's disease; Pathogenesis; Treatment; Update; ALPHA-SYNUCLEIN; NEUROTROPHIC FACTOR; SUBSTANTIA-NIGRA; CONTROLLED-TRIAL; DOPAMINERGIC-NEURONS; RODENT MODELS; GENE-THERAPY; COMPLEX-I; GLUCOCEREBROSIDASE; BRAIN;
D O I：
10.1007/s00415-013-6915-1
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The Parkinson's disease research field is a rapidly moving one, as many of the relevant processes underlying PD neurodegeneration are being deciphered, enabling novel approaches to treatment to be assessed both in the laboratory and in the clinic. This review aims to highlight the most relevant updates in the PD field, with emphasis on research that may help lead towards an improvement in the treatment of this condition.
引用
收藏
页码：1433 / 1440
页数：8
相关论文
共 50 条
  • [1] Parkinson’s disease: an update on pathogenesis and treatment
    Tom Foltynie
    Joshua Kahan
    Journal of Neurology, 2013, 260 : 1433 - 1440
  • [2] Update on the pathogenesis of Parkinson's disease
    Schulz, Joerg B.
    JOURNAL OF NEUROLOGY, 2008, 255 (Suppl 5) : 3 - 7
  • [3] Update on the pathogenesis of Parkinson’s disease
    Jörg B. Schulz
    Journal of Neurology, 2008, 255 : 3 - 7
  • [4] An update on pathogenesis and clinical scenario for Parkinson’s disease: diagnosis and treatment
    Hussaini Adam
    Subash C. B. Gopinath
    M. K. Md Arshad
    Tijjani Adam
    N. A. Parmin
    Irzaman Husein
    Uda Hashim
    3 Biotech, 2023, 13
  • [5] An update on pathogenesis and clinical scenario for Parkinson's disease: diagnosis and treatment
    Adam, Hussaini
    Gopinath, Subash C. B.
    Arshad, M. K. Md
    Adam, Tijjani
    Parmin, N. A.
    Husein, Irzaman
    Hashim, Uda
    3 BIOTECH, 2023, 13 (05)
  • [6] Molecular pathogenesis of Parkinson's disease: update
    Saiki, Shinji
    Sato, Shigeto
    Hattori, Nobutaka
    JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2012, 83 (04): : 430 - 436
  • [7] An update on the treatment of Parkinson's disease
    Jankovic, Joseph
    MOUNT SINAI JOURNAL OF MEDICINE, 2006, 73 (04): : 682 - 689
  • [8] A further update on the role of excitotoxicity in the pathogenesis of Parkinson’s disease
    Giulia Ambrosi
    Silvia Cerri
    Fabio Blandini
    Journal of Neural Transmission, 2014, 121 : 849 - 859
  • [9] An update on the potential role of excitotoxicity in the pathogenesis of Parkinson's disease
    Blandini, Fabio
    FUNCTIONAL NEUROLOGY, 2010, 25 (02) : 65 - 71
  • [10] A further update on the role of excitotoxicity in the pathogenesis of Parkinson's disease
    Ambrosi, Giulia
    Cerri, Silvia
    Blandini, Fabio
    JOURNAL OF NEURAL TRANSMISSION, 2014, 121 (08) : 849 - 859
12345