A PHASE 2, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, ASCENDING DOSE STUDY TO EVALUATE EFFICACY, SAFETY, AND TOLERABILITY OF CC 220 IN SUBJECTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

被引：0
|
作者：
Furie, R. [1 ]
Werth, V. P. [2 ,3 ]
Lee, E. [4 ]
Box, E. [5 ]
Fondal, M. [6 ]
Kivitz, A. [7 ]
Chatham, W. W. [8 ]
Kalunian, K. C. [9 ]
Legerton, C. [10 ]
Anolik, J. H. [11 ]
Korish, S. [12 ]
Hough, D. R. [12 ]
Weiswasser, M. [12 ]
Choi, S. [12 ]
Schafer, P. [12 ]
机构：
[1] Hofstra Northwell Sch Med, Northwell Hlth, Div Rheumatol, New Hyde Pk, NY USA
[2] Hosp Univ Penn, Dept Dermatol, 3400 Spruce St, Philadelphia, PA 19104 USA
[3] Vet Adm Med Ctr, Philadelphia, PA 19104 USA
[4] Inland Rheumatol Clin Trials Inc, Upland, CA USA
[5] Carolinas PLLC, Box Arthrit & Rheumatol, Charlotte, NC USA
[6] Arthrit Res & Treatment Ctr, Stockbridge, GA USA
[7] Altoona Ctr Clin Res, Duncansville, PA USA
[8] Univ Alabama Birmingham, Rheumatol & Clin Immunol, Birmingham, AL USA
[9] UC San Diego Hlth, Div Rheumatol, San Diego, CA USA
[10] Low Country Rheumatol PA, Charleston, SC USA
[11] Univ Rochester, Med Ctr, Div Allergy Immunol & Rheumatol, Rochester, NY 14642 USA
[12] Celgene Corp, Summit, NJ USA
来源：
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY | 2016年 / 34卷 / 04期
关键词：
CC-220; Ikaros; cereblon;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
P5:94
引用
收藏
页码：S77 / S77
页数：1
相关论文
共 50 条
  • [31] A Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study to Evaluate the Efficacy and Safety of RIST4721 in Subjects with Palmoplantar Pustulosis
    Bissonnette, Robert
    Maari, Catherine
    Tsianakas, Athanasios
    Reid, DeAnne
    McCutchan, Sara
    Baumgartner, Scott
    Mackay, James
    Bhakta, Nihar
    DERMATOLOGY AND THERAPY, 2021, 11 (06) : 2179 - 2193
  • [32] A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy, Safety, and Tolerability of Prucalopride in Men With Chronic Constipation
    Yiannakou, Yan
    Piessevaux, Hubert
    Bouchoucha, Michel
    Schiefke, Ingolf
    Filip, Rafal
    Gabalec, Libor
    Dina, Ion
    Stephenson, David
    Kerstens, Rene
    Etherson, Kevin
    Levine, Amy
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2015, 110 (05): : 741 - 748
  • [33] A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 2 TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF CHIGLITAZAR IN NASH PATIENTS
    You, Hong
    Sun, Yameng
    Wu, Cuisong
    Xin, Guijie
    Zhong, Bihui
    Wu, Xiaofeng
    Liu, Yali
    Shi, Junping
    Zhang, Qin
    Zhao, Yingren
    Gao, Yufeng
    Xin, Yongning
    Zhu, Yueyong
    Wu, Lixian
    Mao, Xiaorong
    Du, Jian
    Shang, Jia
    Sun, Weiwei
    Xu, Jie
    Yu, Zujiang
    Nan, Yuemin
    Sheng, Huiping
    Li, Yue
    Rao, Huiying
    Yu, Chaohui
    Wu, Xiaoning
    Tong, Xiaofei
    HEPATOLOGY, 2024, 80 : S1969 - S1970
  • [34] Pneumococcal Vaccination in Patients with Systemic Lupus Erythematosus: A Multicenter Placebo-Controlled Randomized Double-Blind Study
    Grabar, Sophie
    Groh, Matthieu
    Bahuaud, Mathilde
    Costedoat-Chalumeau, Nathalie
    Le Guern, Veronique
    Fior, Renato
    Bienvenu, Boris
    Hachulla, Eric
    Hamidou, Mohamed
    Sibilia, Jean
    Mathian, Alexis
    Hanslik, Thomas
    Guillevin, Loic
    Batteux, Frederic
    Launay, Odile
    ARTHRITIS & RHEUMATOLOGY, 2017, 69
  • [35] Pneumococcal vaccination in patients with systemic lupus erythematosus: A multicenter placebo-controlled randomized double-blind study
    Grabar, Sophie
    Groh, Matthieu
    Bahuaud, Mathilde
    Le Guern, Veronique
    Costedoat-Chalumeau, Nathalie
    Mathian, Alexis
    Hanslik, Thomas
    Guillevin, Loic
    Batteux, Frederic
    Launay, Odile
    VACCINE, 2017, 35 (37) : 4877 - 4885
  • [36] A Phase I, Double-blind, Randomized, Placebo-controlled, Single Dose-escalation Study to Evaluate the Tolerability, and Safety of Cytisinicline in Adult Smokers
    Jacobs, Cindy
    Fonseca, Marlene
    Rigotti, Nancy A.
    Benowitz, Neal
    Clarke, Anthony
    Cain, Dan
    NICOTINE & TOBACCO RESEARCH, 2023, 25 (04) : 814 - 820
  • [37] Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial
    He, Jing
    Zhang, Ruijun
    Shao, Miao
    Zhao, Xiaozhen
    Miao, Miao
    Chen, Jiali
    Liu, Jiajia
    Zhang, Xiaoying
    Zhang, Xia
    Jin, Yuebo
    Wang, Yu
    Zhang, Shilei
    Zhu, Lei
    Jacob, Alexander
    Jia, Rulin
    You, Xujie
    Li, Xue
    Li, Chun
    Zhou, Yunshan
    Yang, Yue
    Ye, Hua
    Liu, Yanying
    Su, Yin
    Shen, Nan
    Alexander, Jessy
    Guo, Jianping
    Ambrus, Julian
    Lin, Xin
    Yu, Di
    Sun, Xiaolin
    Li, Zhanguo
    ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 (01) : 141 - 149
  • [38] Safety, Tolerability and Pharmacokinetics of Dalcetrapib Following Single and Multiple Ascending Doses in Healthy Subjects A Randomized, Double-Blind, Placebo-Controlled, Phase I Study
    Derks, Michael
    Anzures-Cabrera, Judith
    Turnbull, Lynn
    Phelan, Mary
    CLINICAL DRUG INVESTIGATION, 2011, 31 (05) : 325 - 335
  • [39] Omega-3 in Systemic Lupus Erythematosus: A Double-Blind, Placebo-Controlled Randomized Clinical Trial In Systemic Lupus Erythematosus
    Bello, Kayode J.
    Fang, Hong
    Magder, Laurence S.
    Petri, Michelle
    ARTHRITIS AND RHEUMATISM, 2011, 63 (10): : S963 - S963
  • [40] Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus Results of a phase I, placebo-controlled, double-blind, dose-escalation study
    McBride, Jacqueline M.
    Jiang, Jenny
    Abbas, Alexander R.
    Morimoto, Alyssa
    Li, Jing
    Maciuca, Romeo
    Townsend, Michael
    Wallace, Daniel J.
    Kennedy, William P.
    Drappa, Jorn
    ARTHRITIS AND RHEUMATISM, 2012, 64 (11): : 3666 - 3676
12345