Palladium catalyzed direct ortho C-H acylation of 2-arylpyridines using toluene derivatives as acylation reagents

被引：64
|
作者：
Xu, Zhipeng [1 ]
Xiang, Biao [1 ]
Sun, Peipei [1 ,2 ]
机构：
[1] Nanjing Normal Univ, Coll Chem & Mat Sci, Jiangsu Key Lab Biofunct Mat, Nanjing 210097, Jiangsu, Peoples R China
[2] Soochow Univ, Coll Chem Chem Engn & Mat Sci, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Peoples R China
来源：
RSC ADVANCES | 2013年 / 3卷 / 06期
关键词：
BOND ACTIVATION; ORTHO-ARYLATION; SP(2); ACIDS; FUNCTIONALIZATION; ALKYLATION; OXIDATION; ARENES;
D O I：
10.1039/c2ra22208f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A facile ortho-acylation of 2-arylpyridines by a Pd-catalyzed oxidative C-H activation was developed, in which no prefunctionalized toluene derivatives were used as acylation reagents in a tandem reaction to form 2-pyridyldiaryl ketones with moderate yields.
引用
收藏
页码：1679 / 1682
页数：4
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