Palladium catalyzed direct ortho C-H acylation of 2-arylpyridines using toluene derivatives as acylation reagents

被引：64

作者：

Xu, Zhipeng ^{[1
]}

Xiang, Biao ^{[1
]}

Sun, Peipei ^{[1
,2
]}

机构：

[1] Nanjing Normal Univ, Coll Chem & Mat Sci, Jiangsu Key Lab Biofunct Mat, Nanjing 210097, Jiangsu, Peoples R China

[2] Soochow Univ, Coll Chem Chem Engn & Mat Sci, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Peoples R China

来源：

RSC ADVANCES | 2013年 / 3卷 / 06期

关键词：

BOND ACTIVATION; ORTHO-ARYLATION; SP(2); ACIDS; FUNCTIONALIZATION; ALKYLATION; OXIDATION; ARENES;

D O I：

10.1039/c2ra22208f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile ortho-acylation of 2-arylpyridines by a Pd-catalyzed oxidative C-H activation was developed, in which no prefunctionalized toluene derivatives were used as acylation reagents in a tandem reaction to form 2-pyridyldiaryl ketones with moderate yields.

引用

页码：1679 / 1682

页数：4

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