Ambient ionization and miniature mass spectrometry system for chemical and biological analysis

被引：95
|
作者：
Ma, Xiaoxiao [1 ]
Ouyang, Zheng [1 ]
机构：
[1] Purdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47906 USA
来源：
TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2016年 / 85卷
基金：
美国国家科学基金会; 美国国家卫生研究院;
关键词：
Ambient ionization; Miniature mass spectrometer; Biomarker; Therapeutic drug monitoring; Quantitative analysis; DESORPTION ELECTROSPRAY-IONIZATION; HIGH-THROUGHPUT ANALYSIS; DRIED BLOOD SPOTS; PAPER-SPRAY; SURFACE SAMPLING/IONIZATION; INSTRUMENTATION DEVELOPMENT; QUANTITATIVE-ANALYSIS; NANO-ELECTROSPRAY; SAMPLING PROBE; ION-SOURCE;
D O I：
10.1016/j.trac.2016.04.009
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Ambien ionization and miniaturization of mass spectrometers are two fields in mass spectrometry that have advanced significantly in the last decade. The integration of the techniques developed in these two fields is leading to the development of complete miniature analytical systems that can be used for on site or point-of-care analysis by non-expert users. In this review, we report the current status of development in ambient ionization and miniature mass spectrometers, with an emphasis on those techniques with potential impact on the point-of-care (POC) diagnostics. The challenges in the future development of the integrated systems are discussed with possible solutions presented. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：10 / 19
页数：10
相关论文
共 50 条
  • [1] Research Advances in Ambient Ionization and Miniature Mass Spectrometry
    Guo Xiang-Yu
    Huang Xue-Mei
    Zhai Jun-Feng
    Bai Hua
    Li Xiao-Xu
    Ma Xiao-Xiao
    Ma Qiang
    CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2019, 47 (03) : 335 - 346
  • [2] AMBIENT IONIZATION AND MINIATURE MASS SPECTROMETRY: BIOMEDICAL APPLICATIONS
    Cooks, R. G.
    Ouyang, Z.
    Noll, R.
    Manicke, N.
    Costa, A.
    Wu, C.
    Xia, Y.
    Dill, A.
    Ifa, D.
    BIOPOLYMERS, 2009, 92 (04) : 297 - 297
  • [3] Rapid identification of regulated organic chemical compounds in toys using ambient ionization and a miniature mass spectrometry system
    Guo, Xiangyu
    Bai, Hua
    Lv, Yueguang
    Xi, Guangcheng
    Li, Junfang
    Ma, Xiaoxiao
    Ren, Yue
    Zheng Ouyang
    Ma, Qiang
    TALANTA, 2018, 180 : 182 - 192
  • [4] Microextraction for ambient ionization mass spectrometry analysis
    Liu, Yijing
    Shang, Yuhan
    Ma, Qiang
    ADVANCES IN SAMPLE PREPARATION, 2022, 3
  • [5] Ambient Ionization and Miniature Mass Spectrometry Systems for Disease Diagnosis and Therapeutic Monitoring
    Zhang, Wenpeng
    Wang, Xiao
    Xia, Yu
    Ouyang, Zheng
    THERANOSTICS, 2017, 7 (12): : 2968 - 2981
  • [6] Direct identification of prohibited substances in cosmetics and foodstuffs using ambient ionization on a miniature mass spectrometry system
    Ma, Qiang
    Bai, Hua
    Li, Wentao
    Wang, Chao
    Li, Xinshi
    Cooks, R. Graham
    Ouyang, Zheng
    ANALYTICA CHIMICA ACTA, 2016, 912 : 65 - 73
  • [7] Direct Biological Sample Analyses by Laserspray Ionization Miniature Mass Spectrometry
    Zhai, Yanbing
    Liu, Siyu
    Gao, Lijuan
    Hu, Lili
    Xu, Wei
    ANALYTICAL CHEMISTRY, 2018, 90 (09) : 5696 - 5702
  • [8] Ambient Ionization Mass Spectrometry
    Huang, Min-Zong
    Yuan, Cheng-Hui
    Cheng, Sy-Chyi
    Cho, Yi-Tzu
    Shiea, Jentaie
    ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, VOL 3, 2010, 3 : 43 - 65
  • [9] Chemical Aspects of the Extractive Methods of Ambient Ionization Mass Spectrometry
    Badu-Tawiah, Abraham K.
    Eberlin, Livia S.
    Ouyang, Zheng
    Cooks, R. Graham
    ANNUAL REVIEW OF PHYSICAL CHEMISTRY, VOL 64, 2013, 64 : 481 - 505
  • [10] Ambient ionization mass spectrometry
    Lebedev, A. T.
    RUSSIAN CHEMICAL REVIEWS, 2015, 84 (07) : 665 - 692
12345