Research Advances in Ambient Ionization and Miniature Mass Spectrometry

The development and application of ambient ionization and miniature mass spectrometry are current research focus in chemical measurements. The analytical technology based on ambient ionization coupled with miniature mass spectrometry can bypass chromatographic separation and eliminate or simplify sample pretreatment process. The protocol breaks through the drawbacks of labor-intensive and time-consuming of traditional analytical methodologies, and can be used for the rapid and on-site analysis with high sensitivity and high throughput. In this paper, research progress of ambient ionization and miniature mass spectrometry as well as their applications in the fields of food safety, consumer product safety, public security, life science and environmental monitoring have been reviewed, and future trends and prospective have been discussed, which may provide a technical guidance for the researchers engaged in relevant fields.