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Brigham & Womens Hosp, Clin Res Ctr, Robert B Brigham Arthrit & Musculoskeletal, Div Rheumatol Allergy & Immunol, Boston, MA 02115 USA Brigham & Womens Hosp, Clin Res Ctr, Robert B Brigham Arthrit & Musculoskeletal, Div Rheumatol Allergy & Immunol, Boston, MA 02115 USA