THE METABOTROPIC P2Y1 RECEPTOR AS NOVEL DRUG TARGET IN EPILEPSY THE METABOTROPIC P2Y1 RECEPTOR AS NOVEL DRUG TARGET IN EPILEPSY

被引：0
|
作者：
Alves, M. [1 ]
Engel, T. [1 ]
机构：
[1] Royal Coll Sirgeons Ireland, Dublin, Ireland
来源：
PURINERGIC SIGNALLING | 2018年 / 14卷
基金：
爱尔兰科学基金会;
关键词：
Status epilepticus; Epilepsy; P2Y1receptor; Anticonvulsant;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
106
引用
收藏
页码：S119 / S120
页数：2
相关论文
共 50 条
  • [21] Involvement of the P2Y1 receptor in asthmatic airway inflammation
    Maitre, Blandine
    Freund, Monique
    Hechler, Beatrice
    Leon, Catherine
    Heim, Veronique
    Cazenave, Jean-Pierre
    Hanau, Daniel
    Gachet, Christian
    PURINERGIC SIGNALLING, 2008, 4 : S156 - S156
  • [22] Differently expression of the metabotropic P2Y receptor family after hypoxia-induced seizures in neonates and seizure suppression via P2Y1 receptor agonism
    Smith, Jonathon
    Lopez-Avila, Beatriz Gil
    Engel, Tobias
    Mateos, Eva M. Jimenez
    Alves, Mariana
    PURINERGIC SIGNALLING, 2024, 20 (02) : 157 - 162
  • [23] Calmodulin interacts with the platelet ADP receptor P2Y1
    Arthur, Jane F.
    Shen, Yang
    Mu, Fi-Tjen
    Leon, Catherine
    Gachet, Christian
    Berndt, Michael C.
    Andrews, Robert K.
    BIOCHEMICAL JOURNAL, 2006, 398 (339-343) : 339 - 343
  • [24] Study of aggregation of platelets lacking the P2Y1 receptor
    Fabre, JE
    King, BF
    Koller, BH
    DRUG DEVELOPMENT RESEARCH, 2001, 52 (1-2) : 150 - 155
  • [25] Homologous desensitization of the platelet P2Y1 receptor.
    Quinton, TM
    Kunapuli, SP
    BLOOD, 1999, 94 (10) : 67B - 67B
  • [26] Pharmacodynamic interplay of the P2Y1, P2Y12, and TxA2 pathways in platelets: The potential of triple antiplatelet therapy with P2Y1 receptor antagonism
    Oestreich, Julie H.
    Ferraris, Suellen P.
    Steinhubl, Steven R.
    Akers, Wendell S.
    THROMBOSIS RESEARCH, 2013, 131 (02) : E64 - E70
  • [27] Metabotropic P2Y1 receptors inhibit P2X3 receptor-channels in rat dorsal root ganglion neurons
    Gerevich, Z
    Müller, C
    Illes, P
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2005, 521 (1-3) : 34 - 38
  • [28] Developmental expression of metabotropic P2Y1 and P2Y2 receptors in freshly isolated astrocytes from rat hippocampus
    Zhu, YZ
    Kimelberg, HK
    JOURNAL OF NEUROCHEMISTRY, 2001, 77 (02) : 530 - 541
  • [29] Identification of a Promising Drug Candidate for the Treatment of Type 2 Diabetes Based on a P2Y1 Receptor Agonist
    Yelovitch, Shir
    Barr, Haim M.
    Camden, Jean
    Weisman, Gary A.
    Shai, Ela
    Varon, David
    Fischer, Bilha
    JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (17) : 7623 - 7635
  • [30] Synthesis and characterization of [32P]MRS2500, a novel P2Y1 receptor radioligand
    Houston, DV
    Ohno, M
    Jacobson, KA
    Harden, TK
    FASEB JOURNAL, 2005, 19 (05): : A1095 - A1095
12345