The Roles of Moonlighting Proteins in Bacteria

被引：1

作者：

Wang, Guangqiang ^{[1
]}

Xia, Yu ^{[2
]}

Cui, Jing ^{[1
,2
]}

Gu, Zhennan ^{[2
]}

Song, Yuanda ^{[2
]}

Chen, Yong Q. ^{[2
]}

Chen, Haiqin ^{[2
]}

Zhang, Hao ^{[2
]}

Chen, Wei ^{[1
]}

机构：

[1] Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Peoples R China

[2] Jiangnan Univ, Sch Food Sci & Technol, Wuxi 214122, Peoples R China

来源：

CURRENT ISSUES IN MOLECULAR BIOLOGY | 2014年 / 16卷

基金：

中国国家自然科学基金; 国家高技术研究发展计划(863计划);

关键词：

GROUP-A STREPTOCOCCI; ELONGATION-FACTOR TU; HUMAN INTESTINAL MUCUS; ALPHA-ENOLASE BINDS; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE; PLASMINOGEN-BINDING; CELL-SURFACE; LACTOBACILLUS-CRISPATUS; BIFIDOBACTERIUM STRAINS; COMPETITIVE-EXCLUSION;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Moonlighting proteins, characterized by their multiple autonomous functions, have been detected in bacteria. Surprisingly, many of these proteins are conserved and involved in metabolic pathway or the cell stress response. They localise to the bacterial surface to take on additional activities, which have been hypothesised to contribute to bacterial virulence or bacterial benefit. In this review, we compare the functions of moonlighting proteins in bacteria, describe the structural basis of moonlighting functions, and summarise the regulation of secretion and localisation of moonlighting proteins.

引用

页码：15 / 22

页数：8

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