Neutralization of murine myeloid suppressor cells enhances the efficacy of GD2-specific CAR T cells directed against human sarcoma in a xenograft model

被引：0

作者：

Highfill, Steven ^{[1
]}

Smith, Jillian ^{[1
]}

Long, Adrienne ^{[1
]}

Cui, Yongzhi ^{[1
]}

Orentas, Rimas ^{[1
]}

Mackail, Crystal ^{[1
]}

机构：

[1] NCI, Pediat Oncol Branch, Bethesda, MD 20892 USA

来源：

JOURNAL OF IMMUNOLOGY | 2014年 / 192卷

关键词：

D O I：

暂无

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

VAC11P1010

引用

页数：2

共 50 条

[31] Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G
Kailayangiri, Sareetha
Altvater, Bianca
Spurny, Christian
Jamitzky, Silke
Schelhaas, Sonja
Jacobs, Andreas H.
Wiek, Constanze
Roellecke, Katharina
Hanenberg, Helmut
Hartmann, Wolfgang
Wiendl, Heinz
Pankratz, Susann
Meltzer, Jutta
Farwick, Nicole
Greune, Lea
Fluegge, Maike
Rossig, Claudia
ONCOIMMUNOLOGY, 2017, 6 (01):
[32] Selectively targeting myeloid-derived suppressor cells through TRAIL receptor 2 to enhance the efficacy of CAR T cell therapy for treatment of breast cancer
Nalawade, Saisha A.
Shafer, Paul
Bajgain, Pradip
McKenna, Mary K.
Ali, Arushana
Kelly, Lauren
Joubert, Jarrett
Gottschalk, Stephen
Watanabe, Norihiro
Leen, Ann
Parihar, Robin
Vera Valdes, Juan Fernando
Hoyos, Valentina
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 9 (11)
[33] Bevacizumab-mediated tumor vasculature remodelling improves tumor infiltration and antitumor efficacy of GD2-CAR T cells in a human neuroblastoma preclinical model
Bocca, Paola
Di Carlo, Emma
Caruana, Ignazio
Emionite, Laura
Cilli, Michele
De Angelis, Biagio
Quintarelli, Concetta
Pezzolo, Annalisa
Raffaghello, Lizzia
Morandi, Fabio
Locatelli, Franco
Pistoia, Vito
Prigione, Ignazia
ONCOIMMUNOLOGY, 2018, 7 (01):
[34] Doxorubicin eliminates tumor-induced myeloid-derived suppressor cells and enhances T-helper lymphocyte-based immunotherapy in a murine breast cancer model
Alizadeh, Darya
Trad, Malika
Katsanis, Emmanuel
Larmonier, Nicolas
CANCER RESEARCH, 2013, 73 (08)
[35] GD2-specific CAR T Cells Undergo Potent Activation and Deletion Following Antigen Encounter but can be Protected From Activation-induced Cell Death by PD-1 Blockade
Gargett, Tessa
Yu, Wenbo
Dotti, Gianpietro
Yvon, Eric S.
Christo, Susan N.
Hayball, John D.
Lewis, Ian D.
Brenner, Malcolm K.
Brown, Michael P.
MOLECULAR THERAPY, 2016, 24 (06) : 1135 - 1149
[36] Enhanced anti-tumor efficacy of "IL-15 and CCL19" -secreting CAR-T cells in human glioblastoma orthotopic xenograft model
Chen, Wanqiong
Hong, Limian
Lin, Shaomei
Xian, Na
Yan, Cailing
Zhao, Ningning
Xiao, Yonglei
Liao, Wanting
Huang, Yuxiang
Chen, Mingzhu
FRONTIERS IN ONCOLOGY, 2025, 15
[37] Potent and Target Specific Cytotoxicity of PRAME TCR Mimic CAR T Cells in KMT2A-Rearranged AML Patient-Derived Xenograft Model
Kirkey, Danielle C.
Robinson, Leila
Hylkema, Tiffany
Loeb, Anisha
Ries, Rhonda E.
Mckay, Cyd
Root, Christina
Pardo, Laura
Loeb, Keith R.
Le, Quy
Scheinberg, David A.
Meshinchi, Soheil
BLOOD, 2023, 142
[38] Tumor -derived indoleamine 2,3-dioxygenase regulates density of tumor infiltrating CD8+ T cells and myeloid derived suppressor cells in a murine model of ovarian cancer
Amobi, Adaobi
Odunsi, Kunle
JOURNAL OF IMMUNOLOGY, 2017, 198 (01):
[39] GD2-directed CAR-T cells in combination with HGF-targeted neutralizing antibody (AMG102) prevent primary tumor growth and metastasis in Ewing sarcoma
Charan, Manish
Dravid, Piyush
Cam, Maren
Audino, Anthony
Gross, Amy C.
Arnold, Michael A.
Roberts, Ryan D.
Cripe, Timothy P.
Pertsemlidis, Alexander
Houghton, Peter J.
Cam, Hakan
INTERNATIONAL JOURNAL OF CANCER, 2020, 146 (11) : 3184 - 3195
[40] CD4 depletion enhances the efficacy of Super2 IL-33 armored CAR T cell against solid tumors and leads memory formation of both endogenous and CAR T cells
Mohamed, Asmaa
Ferry, Shannon Lynn
Huang, Yina H.
JOURNAL OF IMMUNOLOGY, 2023, 210 (01):

← 1 2 3 4 5 →