BrOnsted Acid-Catalyzed Friedel-Crafts Reaction of Indoles to -Ketimino Esters

被引：6
|
作者：
Yang, Jin-Hui [1 ,2 ]
Lou, Qin-Xin [1 ]
Chen, Yan-Xue [1 ,2 ]
Tang, Kang-Kang [1 ]
机构：
[1] Shijiazhuang Tiedao Univ, Sch Mat Sci & Engn, Shijiazhuang, Hebei Province, Peoples R China
[2] Hebei Prov Key Lab Traff Engn Mat, Shijiazhuang, Hebei Province, Peoples R China
来源：
SYNTHETIC COMMUNICATIONS | 2015年 / 45卷 / 16期
关键词：
BrOnsted acid; Friedel-Crafts reaction; indoles; -ketimino esters; HIGHLY DIASTEREOSELECTIVE SYNTHESIS; ARYLGLYCINE DERIVATIVES; IMINO ESTERS; DRAGMACIDIN; REDUCTION; ALKALOIDS; PHENOLS;
D O I：
10.1080/00397911.2015.1039033
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Friedel-Crafts reaction of indoles to aromatic -ketimino esters was found to be catalyzed by camphorsulfonic acid with good yields (up to 98%) under ambient temperature. This process provides an efficient method for the synthesis of unnatural amino acid derivatives that bear quaternary carbon centers.
引用
收藏
页码：1887 / 1892
页数：6
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