Diesel exhaust exposure, its multi-system effects, and the effect of new technology diesel exhaust

被引：50
|
作者：
Reis, Haley [2 ]
Reis, Cesar [1 ,2 ]
Sharip, Akbar [3 ]
Reis, Wenes [1 ]
Zhao, Yong [4 ,5 ,6 ]
Sinclair, Ryan [7 ]
Beeson, Lawrence [8 ]
机构：
[1] Loma Linda Univ, Med Ctr, Dept Prevent Med, 24785 Stewart St,Suite 204, Loma Linda, CA 92354 USA
[2] Loma Linda Univ, Sch Med, 11175 Campus St, Loma Linda, CA 92350 USA
[3] Loma Linda Univ, Med Ctr, Dept Occupat Med, 328 East Commercial Rd,Suite 101, San Bernardino, CA 92408 USA
[4] Chongqing Med Univ, Sch Publ Hlth & Management, Chongqing, Peoples R China
[5] Chongqing Med Univ, Res Ctr Med & Social Dev, Chongqing, Peoples R China
[6] Chongqing Med Univ, Innovat Ctr Social Risk Governance Hlth, Chongqing, Peoples R China
[7] Loma Linda Univ, Sch Publ Hlth, Ctr Community Resilience, Loma Linda, CA 92350 USA
[8] Loma Linda Univ, Sch Publ Hlth, Ctr Nutr Hlth Lifestyle & Dis Prevent, Loma Linda, CA 92350 USA
来源：
ENVIRONMENT INTERNATIONAL | 2018年 / 114卷
关键词：
Diesel exhaust; Diesel exhaust particles; Air pollution; Eyes; Kidney; Cardiovascular; Respiratory; Central nervous system; Hematopoietic; New technology diesel exhaust; LONG-TERM EXPOSURE; PARTICULATE MATTER EXPOSURE; OUTDOOR AIR-POLLUTION; NERVOUS-SYSTEM TUMORS; ENGINE EXHAUST; BENZENE EXPOSURE; LUNG-CANCER; INFLAMMATORY RESPONSES; RESIDENTIAL PROXIMITY; OCCUPATIONAL-EXPOSURE;
D O I：
10.1016/j.envint.2018.02.042
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Exposure to diesel exhaust (DE) from vehicles and industry is hazardous and affects proper function of organ systems. DE can interfere with normal physiology after acute and chronic exposure to particulate matter (PM). Exposure leads to potential systemic disease processes in the central nervous, visual, hematopoietic, respiratory, cardiovascular, and renal systems. In this review, we give an overview of the epidemiological evidence supporting the harmful effects of diesel exhaust, and the numerous animal studies conducted to investigate the specific pathophysiological mechanisms behind DE exposure. Additionally, this review includes a summary of studies that used biomarkers as an indication of biological plausibility, and also studies evaluating new technology diesel exhaust (NTDE) and its systemic effects. Lastly, this review includes new approaches to improving DE emissions, and emphasizes the importance of ongoing study in this field of environmental health.
引用
收藏
页码：252 / 265
页数：14
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