Myeloproliferative disease induced by leukemogenic Ptpn11 (Shp-2) phosphatase arises from hematopoietic stem cells

被引：0
|
作者：
Xu, Dan
Wang, Siying
Yu, Wen-Mei
Chan, Gordon
Araki, Toshiyuki
Bunting, Kevin D.
Neel, Benjamin G.
Qu, Cheng-Kui
机构：
来源：
CANCER RESEARCH | 2010年 / 70卷
关键词：
D O I：
10.1158/1538-7445.AM10-4296A
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
4296A
引用
收藏
页数：3
相关论文
共 50 条
  • [31] Association between serum pepsinogens and polymorphism of Ptpn11 encoding Shp-2 among Helicobacter Pylori sercipositive Japanese
    Ando, T
    Goto, Y
    Yamamoto, K
    Tamakoshi, A
    El-Omar, E
    Kusugami, K
    Goto, H
    GASTROENTEROLOGY, 2005, 128 (04) : A8 - A8
  • [32] SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans
    Liu, Kun-Wei
    Feng, Haizhong
    Bachoo, Robert
    Kazlauskas, Andrius
    Smith, Erin M.
    Symes, Karen
    Hamilton, Ronald L.
    Nagane, Motoo
    Nishikawa, Ryo
    Hu, Bo
    Cheng, Shi-Yuan
    JOURNAL OF CLINICAL INVESTIGATION, 2011, 121 (03): : 905 - 917
  • [33] SHP-2/PTPN11 MEDIATES GLIOMAGENESIS DRIVEN BY PDGFRA AND INK4A/ARF ABERRATIONS IN MICE AND HUMANS
    Liu, Kun-wei
    Feng, Haizhonog
    Bachoo, Robert
    Kazlauskas, Andrius
    Smith, Erin M.
    Symes, Karen
    Hamilton, Ronald L.
    Nagane, Motoo
    Nishikawa, Ryo
    Hu, Bo
    Cheng, Shi-Yuan
    NEURO-ONCOLOGY, 2011, 13 : 14 - 14
  • [34] Molecular analysis of PTPN11 gene encoding, protein tyrosine phosphatase SHP-2 and phenotype-genotype correlation in Japanese patients with Noonan syndrome.
    Aoki, Y
    Niihori, T
    Yang, X
    Kurosawa, K
    Ohashi, H
    Kondo, T
    Ishii, E
    Suzuki, Y
    Kure, S
    Matsubara, Y
    AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (04) : 527 - 527
  • [35] Non-Lineage/Stage Restricted Effects of a Gain-of-Function Mutation in Tyrosine Phosphatase Ptpn11 (Shp2) on Malignant Transformation of Hematopoietic Cells
    Xu, Dan
    Liu, Xia
    Yu, Wen-Mei
    Meyerson, Howard J.
    Gerson, Stanton L.
    Qu, Cheng-Kui
    BLOOD, 2011, 118 (21) : 181 - 181
  • [36] Protein Tyrosine Phosphatase Shp2 (Ptpn11) Plays an Important Role in Maintenance of Chromosome Stability
    Liu, Xia
    Zheng, Hong
    Qu, Cheng-Kui
    CANCER RESEARCH, 2012, 72 (20) : 5296 - 5306
  • [37] Tyrosine phosphatase PTPN11/SHP2 in solid tumors - bull's eye for targeted therapy?
    Chen, Xun
    Keller, Steffen Johannes
    Hafner, Philipp
    Alrawashdeh, Asma Y.
    Avery, Thomas Yul
    Norona, Johana
    Zhou, Jinxue
    Ruess, Dietrich Alexander
    FRONTIERS IN IMMUNOLOGY, 2024, 15
  • [38] Non-lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatase Ptpn11 (Shp2) on malignant transformation of hematopoietic cells
    Xu, Dan
    Liu, Xia
    Yu, Wen-Mei
    Meyerson, Howard J.
    Guo, Caiying
    Gerson, Stanton L.
    Qu, Cheng-Kui
    JOURNAL OF EXPERIMENTAL MEDICINE, 2011, 208 (10): : 1977 - 1988
  • [39] Gain-of-function/Noonan syndrome SHP-2/Ptpn11 mutants enhance calcium oscillations and impair NFAT signaling
    Uhlén, P
    Burch, PM
    Zito, CL
    Estrada, M
    Ehrlich, BE
    Bennett, AM
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (07) : 2160 - 2165
  • [40] SHP-2/PTPN11 IS A CRITICAL MEDIATOR OF GLIOMAGENESIS DRIVEN BY PDGFR-ALPHA AND INK4A/ARF ABERRATIONS
    Cheng, Shiyuan
    Lin, Kunwei
    Feng, Haizhong
    Bacho, Robert
    Kazlauskas, Andrius
    Smith, Erin M.
    Symes, Karen
    Hu, Bo
    NEURO-ONCOLOGY, 2010, 12 : 11 - 11
12345