Hypoxia Inducible Factor-1 Upregulates the Expression of Plasminogen Activator Inhibitor-1 in Retinal Endothelial Cells to Promote their Survival in Proliferative Diabetic Retinopathy Patients

被引:0
|
作者
Hassan, Syed Junaid [1 ]
Babapoor, Savalan [1 ]
Jee, Kathleen Josephine [1 ]
Puchner, Brooks [1 ]
Deshpande, Monika [1 ]
Semenza, Gregg L. [1 ]
Montaner, Silvia [2 ]
Sodhi, Akrit [1 ]
机构
[1] Johns Hopkins Sch Med, Wilmer Eye Inst, Clarksville, MD USA
[2] Univ Maryland, Sch Med, Baltimore, MD 21201 USA
关键词
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
4282
引用
收藏
页数:3
相关论文
共 50 条
  • [41] Modulation of tissue plasminogen activator and plasminogen activator inhibitor-1 by transforming growth factor-β in human retinal glial cells
    Schacke, W
    Beck, KF
    Pfeilschifter, J
    Koch, F
    Hattenbach, LO
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2002, 43 (08) : 2799 - 2805
  • [42] Suppression of SPARC in human trabecular meshwork cells upregulates Plasminogen Activator Inhibitor-1
    MacDonald, William
    Kang, Min Hyung
    Rhee, Douglas J.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2019, 60 (09)
  • [43] Increased expression of plasminogen activator inhibitor-1 in R-rickettsii-infected endothelial cells
    Shi, RJ
    SimpsonHaidaris, PJ
    Marder, VJ
    Silverman, DJ
    Sporn, LA
    THROMBOSIS AND HAEMOSTASIS, 1996, 75 (04) : 600 - 606
  • [44] Hypoxia enhances the expression of plasminogen activator inhibitor-1 in human lung cancer cells, EBC-1
    Kimura, D
    Imaizumi, T
    Tamo, W
    Sakai, T
    Ito, K
    Hatanaka, R
    Yoshida, H
    Tsushima, T
    Satoh, K
    Fukuda, I
    TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 2002, 196 (04): : 259 - 267
  • [45] Green tea polyphenols inhibit plasminogen activator inhibitor-1 expression and secretion in endothelial cells
    Liu, J.
    Ying, C.
    Zuo, X.
    Meng, Y.
    Yi, W.
    Fan, Z.
    JOURNAL OF HYPERTENSION, 2008, 26 : S388 - S388
  • [46] Green tea polyphenols inhibit plasminogen activator inhibitor-1 expression and secretion in endothelial cells
    Liu, Jian
    Ying, Chenjiang
    Meng, Yi
    Yi, Weijie
    Fan, Zhiliang
    Zuo, Xuezhi
    Tian, Chong
    Sun, Xiufa
    BLOOD COAGULATION & FIBRINOLYSIS, 2009, 20 (07) : 552 - 557
  • [47] Plasma Plasminogen Activator Inhibitor-1 Is Associated with End-Stage Proliferative Diabetic Retinopathy in the Northern Chinese Han Population
    Zhong, Ze-Long
    Chen, Song
    EXPERIMENTAL DIABETES RESEARCH, 2012,
  • [48] Cerivastatin reduced plasminogen activator inhibitor-1 and endothelin-1 expression and increased endothelial NOS expression in vascular endothelial cells
    Uchiyama, T
    Kurabayashi, M
    Ohyama, Y
    Utsugi, T
    Ito, H
    Tsuchida, A
    Ohno, T
    Ito, Y
    Nakamura, T
    Tomono, S
    Kawazu, S
    Nagai, R
    DIABETES, 2000, 49 : A213 - A213
  • [49] The involvement of hypoxia-inducible factor-1 in the regulation of plasminogen activator inhibitor type 1 promoter under hypoxia in human keloid fibroblasts
    Wu, Y
    Zhang, Q
    Kelly, P
    Messadi, DD
    Tuan, T
    Le, AD
    MOLECULAR BIOLOGY OF THE CELL, 2002, 13 : 205A - 206A
  • [50] Inhibition of Plasminogen Activator Inhibitor-1 (PAI-1) Corrects Diabetic Endothelial Progenitor Cells (EPC) Dysfunction
    Grant, Maria B.
    Hazra, Sugata
    Bhatwadekar, Ashay D.
    Bartelmez, Stephen
    Higgins, Paul J.
    Boulton, Michael E.
    DIABETES, 2010, 59 : A63 - A63