Designed mimics of islet amyloid polypeptide as inhibitors of protein aggregation and cell degeneration in Alzheimer's disease and type 2 diabetes

被引:0
|
作者
Yan, L-M [1 ]
Velkova, A. [1 ]
Tatarek-Nossol, M. [2 ]
Kracklauer, M. [1 ]
Bakou, M. [1 ]
Andreetto, E. [1 ]
Kapurniotu, A. [1 ]
机构
[1] Tech Univ Munich, Div Peptide Biochem, Freising Weihenstephan, Germany
[2] Rhein Westfal TH Aachen, Inst Biochem & Mol Cell Biol, Aachen, Germany
关键词
IAPP;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:S56 / S57
页数:2
相关论文
共 50 条
  • [31] Ruthenium complexes as inhibitors of human islet amyloid polypeptide aggregation, an effect that prevents beta cell apoptosis
    Ma, Lijuan
    Fu, Yuanting
    Yu, Lianling
    Li, Xiaoling
    Zheng, Wenjie
    Chen, Tianfeng
    RSC ADVANCES, 2015, 5 (23) : 17405 - 17412
  • [32] Polyoxometalates as Inhibitors of the Aggregation of Amyloid β Peptides Associated with Alzheimer's Disease
    Geng, Jie
    Li, Meng
    Ren, Jinsong
    Wang, Enbo
    Qu, Xiaogang
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (18) : 4184 - 4188
  • [33] Islet amyloid polypeptide gene promoter polymorphisms are not associated with Type 2 diabetes or with the Eseverity of islet amyloidosis
    Esapa, C
    Moffitt, JH
    Novials, A
    McNamara, CM
    Levy, JC
    Laakso, M
    Gomis, R
    Clark, A
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2005, 1740 (01): : 74 - 78
  • [34] Intrinsically Disordered Islet Amyloid Polypeptide Is a Pathogenic Link Between Type-2 diabetes and Heart Disease
    Despa, Sanda
    Koch, Brian
    Margulies, Kennetth B.
    Bers, Donald
    Despa, Florin
    BIOPHYSICAL JOURNAL, 2011, 100 (03) : 229 - 229
  • [35] Nanoparticles and Nanocolloidal Carbon: Will They Be the Next Antidiabetic Class That Targets Fibrillation and Aggregation of Human Islet Amyloid Polypeptide in Type 2 Diabetes?
    Szunerits, Sabine
    Abderrahmani, Amar
    Boukherroub, Rabah
    ACCOUNTS OF CHEMICAL RESEARCH, 2022, 55 (20) : 2869 - 2881
  • [36] Human islet amyloid polypeptide: A therapeutic target for the management of type 2 diabetes mellitus
    Roham, Pratiksha H.
    Save, Shreyada N.
    Sharma, Shilpy
    JOURNAL OF PHARMACEUTICAL ANALYSIS, 2022, 12 (04) : 556 - 569
  • [37] The role of Islet Amyloid PolyPeptide (IAPP)-membrane interactions in type 2 diabetes mellitus
    Engel, MFM
    de Kruijff, B
    Höppener, JWM
    Killian, JA
    FEBS JOURNAL, 2005, 272 : 236 - 236
  • [38] Copper Coordination Features of Human Islet Amyloid Polypeptide: The Type 2 Diabetes Peptide
    Sanchez-Lopez, Carolina
    Cortes-Mejia, Rodrigo
    Miotto, Marco C.
    Binolfi, Andres
    Fernandez, Claudio O.
    del Campo, Jorge M.
    Quintanar, Liliana
    INORGANIC CHEMISTRY, 2016, 55 (20) : 10727 - 10740
  • [39] Levels of islet amyloid polypeptide in cerebrospinal fluid and plasma from patients with Alzheimer's disease
    Schultz, Nina
    Janelidze, Shorena
    Byman, Elin
    Minthon, Lennart
    Nagga, Katarina
    Hansson, Oskar
    Wennstrom, Malin
    PLOS ONE, 2019, 14 (06):
  • [40] Ameliorating amyloid aggregation through osmolytes as a probable therapeutic molecule against Alzheimer's disease and type 2 diabetes
    Kumari, Anchala
    Somvanshi, Pallavi
    Grover, Abhinav
    RSC ADVANCES, 2020, 10 (21) : 12166 - 12182