Comparative effectiveness research: does one size fit all?

被引:5
|
作者
Kunz, Lauren M. [2 ]
Yeh, Robert W. [3 ,4 ]
Normand, Sharon-Lise T. [1 ,2 ]
机构
[1] Harvard Univ, Sch Med, Dept Hlth Care Policy, Boston, MA 02115 USA
[2] Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA
[3] Massachusetts Gen Hosp, Boston, MA 02114 USA
[4] Harvard Clin Res Inst, Boston, MA USA
关键词
ENDARTERECTOMY; ANGIOPLASTY; OUTCOMES;
D O I
10.1002/sim.5482
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In this commentary, we argue that although randomization has many benefits, not all questions we seek to answer fit into a randomized setting. Our argument utilizes the clinical setting of carotid atherosclerosis management where specific clinical questions are answered by using a variety of comparative effectiveness designs. Observational studies should not be ruled out when designing studies to address questions of comparative effectiveness. Copyright (c) 2012 John Wiley & Sons, Ltd.
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页码:3062 / 3065
页数:4
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