Antibacterial constituents against Helicobacter pylori of Brazilian medicinal plant, pariparoba

被引：23
|
作者：
Isobe, T
Ohsaki, A
Nagata, K
机构：
[1] Hyogo Med Univ, Dept Chem, Nishinomiya, Hyogo 6638501, Japan
[2] Hyogo Med Univ, Dept Bacteriol, Nishinomiya, Hyogo 6638501, Japan
[3] Tokyo Med & Dent Univ, Inst Biomat & Bioengn, Chiyoda Ku, Tokyo 1010062, Japan
来源：
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN | 2002年 / 122卷 / 04期
关键词：
Helicobacter pylori; N-benzoylmescaline; Pothomorphe umbellata; Pariparoba; Piperaceac; wogonin; uvangoletin;
D O I：
10.1248/yakushi.122.291
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Four known compounds have been isolated from the aerial parts of the Brazilian medicinal plant Pariparoba (Pothomorphe umbellata). They were an alkaloid, a flavone, a dihydrocalcone, and a steroid. The chemical structures were established to be N-benzoylmescaline, wogonin, uvangoletin, and beta-sitosterol glucoside using spectral methods. Among these compounds, the main component N-benzoylmescaline showed significant antibacterial activity against Helicobacter pylori.
引用
收藏
页码：291 / 294
页数：4
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